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Endocrine Abstracts

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World Congress on Clinical Trials in Diabetes

Abstract Topics

Regulatory Trends in Diabetes

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Pediatric Investigational Plan (PIP)
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Translational and Preclinical Trend in Diabetes

ea0043oc45 | Regulatory Trends in Diabetes | WCTD2016

Effect of curcumin supplementation on anthropometric measurements in patients with type 2 diabetes

Adibian Mahsa , Hodai Homa , Sohrab Golbon

Objective: Curcumin is the main natural polyphenol found in the rhizome of Curcuma longa (turmeric). Experimental evidence supports the activity of curcumin in promoting weight loss. This double blind randomized, controlled study aims to evaluate the effect of curcumin on anthropometric measurements in patients with type 2 diabetes.Methods: About 44 subjects were randomly assigned to receive either curcumin or placebo capsules for 10 weeks. The patients ...
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ea0043oc46 | Regulatory Trends in Diabetes | WCTD2016

The role of plant natural products in diabetes drug discovery and development: A report with focus on Nigerian biodiversity

Ajiboye Abdulfatai Temitope , Asekun Olayinka Taiwo , Familoni Oluwole B.

Background: Diabetes mellitus (DM) is a metabolic disorder resulting from a defect in insulin secretion, insulin action, or both. Insulin deficiency in turn leads to chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism. DM affects most of the people in both developed and developing countries. The treatment of diabetes with conventional drugs is very expensive and chances of side effects are high.Plant natural products have...
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ea0043oc47 | Regulatory Trends in Diabetes | WCTD2016

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ea0043oc48 | Regulatory Trends in Diabetes | WCTD2016

Effects of Telemedicine Intervention on Exercise Capacity and Quality of Life in Patients with Tip II Diabetes Mellitus

Duruturk Neslihan , Acar Manolya , Dogan Merve , Gulen Merve , Gulbaz Gamze K. , Gorgulu Meltem , Ertekin Z Tugce

Background: Exercise training has become an important adjunct therapy for both the prevention and management of type II diabetes mellitus. Interest in telemedicine is increasing as a potentially innovative and sustainable intervention approach to diabetes management. Telemedicine can facilitate the achievement of individualized treatment goals by training patients to manage their own disease.Objective: To evaluate the effect of telemedicine on exercise c...
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ea0043oc49 | Regulatory Trends in Diabetes | WCTD2016

Modulating effects of omega-3 fatty acids and pioglitazone combination on insulin resistance through toll-like receptor 4 in type 2 diabetes mellitus

Eissa Laila , Eraky Salma , Mansour Noha

Toll-like receptor 4 (TLR-4) plays an important role in innate immunity. Changes in the reduction–oxidation balance of tissues can lead to a pro-inflammatory state and insulin resistance typically seen in diabetes. An action thought to be mediated by TLRs. Omega-3 fatty acids and peroxisome proliferator activated receptor gamma (PPAR-γ) agonists as pioglitazone are currently used for decreasing inflammation in diabetes.Aim: The aim of this stud...
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ea0043oc50 | Regulatory Trends in Diabetes | WCTD2016

Electrospun polyvinyl alcohol/ pluronic F127 blended nanofibers containing titanium dioxide for antibacterial wound dressing

El-Aassar Mohamed , El Fawal G.F. , El-Deeb Nehal , Shokry Hassan , Mo Xiumei

In this study, an antibacterial electrospun nanofibers for wound dressing application was successfully prepared from polyvinyl alcohol (PVA), Pluronic F127 (Plur), polyethyleneimine (PEI) blend solution with titanium dioxide nanoparticles (TiO2NPs). PVA–Plur–PEI nanofibers containing various ratios of TiO2 NPs were obtained. The formation and presence of TiO2 in the PVA–Plu–PEI/TiO2 composite was confirmed by X-ra...
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ea0043oc51 | Regulatory Trends in Diabetes | WCTD2016

Effects of curcumin supplementation on BMI and blood pressure in patients with type 2 diabetes

Hodai Homa , Adibian Mahsa , Sohrab Golbon

Objective: Diabetes and hypertension frequently occur together. Obesity, inflammation, oxidative stress, and insulin resistance are thought to be the main risk factors for them. Several spices have been shown to exhibit activity against hypertension and obesity through antioxidant and anti-inlammatory mechanisms. Among them curcumin has shown to be non-toxic and exhibits various bio-logical activities such as anti-oxidant and anti-inflammatory effects. This study was designed ...
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ea0043oc52 | Regulatory Trends in Diabetes | WCTD2016

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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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