Endocrine Abstracts

Introduction: Anthropometric studies are one of the methods, by means of which it is possible to assess patient’s nutritional status.

Aim: The aim of this study was to assess the relationship between the selected anthropometric as well as biochemical parameters and CRP- reactive protein concentration among patients with endocrine disorders.

Materials and methods: The studied group involved all patients hospitalized at the Endocrinology Department in the Piekary Medical Centre in Piekary Ślęskie from 2nd January 2012 to 31st December 2012 who met the inclusion criteria - 299 subjects (264 women and 35 men). Anthropometric studies and body composition analysis were carried out and results of biological parameters were analysed. The following indices were measured: BMI, WHR, WHtR and biochemical tests as follows: 25(OH)D₃, CRP and lipid profile. The study was retrospective and non-interventional. α=0.05.

Results: Overweight or obesity was observed among 63% group (N=188) based of BMI score. Deficiency or serious deficiency of vitamin D was observed among 84% group. The mean concentration of 25(OH)D₃ was 20.3±8.3 ng/ml; CRP reactive protein 4.7±7.4 mg/l; total cholesterol 212.1±45.4 mg/dl; LDL cholesterol 124.9±42.4 mg/dl; HDL cholesterol 61.5±19.3 mg/dl; triglycerides 135.4±76.3 mg/dl. 36% of patients were found to have high concentrations of CRP. There were observed positive correlation between BMI and CRP-reactive protein (R=0.33; P<0.0001); WHtR and CRP-reactive protein (R=0.38; P<0.0001); WHR and CRP-reactive protein (R=0.26; P<0.0001); percentage of body fat and CRP-reactive protein (R=0.26; P<0.001); waist circumference and CRP-reactive protein (R=0.26; P<0.0001).

Conclusions: Induction of inflammation was observed in all patients with abnormal body weight. Inflammation intensity (determined on the basis of CRP-concentration) was higher in overweight than obese patients.