ECE2016 Eposter Presentations Obesity (69 abstracts)
Obstructive sleep apnoea syndrome – longitudinal outcomes and improvement predictors after bariatric surgery
Rita Bettencourt-Silva 1, , Daniela Magalhães 1, , Pedro Souteiro 1, , João Sérgio Neves 1, , Sofia Castro Oliveira 1, , Maria Manuel Costa 1, , Ana Saavedra 1, , Marília Bettencourt-Silva 3 , Leonor Almeida 4 , Marta Drummond 2, , Joana Queirós 1, , Ana Varela 1, , Paula Freitas 1, , Flora Correia 2, , Davide Carvalho 1, & Davide AMTCO group 1
1Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, EPE, Porto, Portugal; 2Faculty of Medicine, University of Porto, Porto, Portugal; 3Institute of Hygiene and Tropical Medicine, New University of Lisbon, Lisbon, Portugal; 4Department of Pneumonology, Centro Hospitalar São João, EPE, Porto, Portugal; 5Multidisciplinary Group for Surgical Management of Obesity, Centro Hospitalar São João, Porto, Portugal; 6Faculty of Nutrition and Food Science, University of Porto, Porto, Portugal.
Background: Bariatric surgery has been associated with a decrease in multiple obesity-related comorbidities including obstructive sleep apnoea syndrome (OSA). This study aims to access the OSA evolution in obese patients who underwent bariatric surgery.
Methods: Retrospective longitudinal study of a population of obese patients who underwent bariatric surgery between January/2010 and July/2014 in our centre. Only patients who have undergone polysomnography both before and after surgery were included. We have evaluated anthropometric, metabolic and polysomnographic data.
Results: A total of 78 patients were included, 56 (71.8%) were female, with a median age of 51 years (interquartile range[IQR] 46.25–51.00), body mass index (BMI) of 44.04 kg/m2 (IQR 40.56–49.17) and apnoea-hypopnoea index (AHI) of 36.90 events/hour (IQR 23.40–52.15). In the preoperative evaluation, 7.7% had mild, 33.3% moderate and 59% severe OSA. The majority of them (74.4%) were treated with continuous positive airway pressure and 20.5% were on bi-level non-invasive ventilation. After surgery (median revaluation time was 11 months) there were statistically significant reductions in AHI (36.9 vs. 11.4; P<0.001), Epworth Sleepiness Scale (8 vs. 5; P<0.001), sleep time with oxygen saturation below 90% (24.9 vs. 3.2; P<0.001) and desaturation index (31.40 vs. 8.55; P<0.001) and significant elevations in mean (91 vs. 93.55; P<0.001) and minimum (71.50 vs. 83; P<0.001) oxygen saturation. There was an improvement in OSA severity in 37 (47.4%) patients and OSA resolution in 13 (16.7%) patients. Only 43.6% continued to be treated with positive airway pressure. The AHI improvement was positively correlated with BMI reduction (r=0.296; P=0.009), total weight loss (r=0.289; P=0.010) and weight loss percentage (r=0.249; P=0.028) and negatively correlated with preoperative values of AHI (r=−0.792; P<0.001), BMI (r=−0.259; P=0.022) and weight (r=−0.267; P=0.018). After adjusting for age and sex, BMI reduction (β=1.217; P=0.014), weight loss (β=0.418; P=0.035), initial AHI (β=−0.840, P<0.001) and initial BMI (β=−1.093; P=0.017) were predictive of the AHI improvement.
Conclusion: Bariatric surgery has beneficial effect on OSA outcome. This effect seems to be dependent on weight loss and on the preoperative values of AHI and BMI.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more