ECE2016 Eposter Presentations Diabetes (to include epidemiology, pathophysiology) (83 abstracts)
Characterization of a pediatric population with type 1 diabetes at transition to adult health care
Joana Oliveira 1, , Mariana Domingues 3 , Sandra Belo 1, , Joana Serra Caetano 2 , Rita Cardoso 2 , Isabel Dinis 2 , Nanci Baptista 2 , Paula Freitas 1, , Davide Carvalho 1, & Alice Mirante 2
1Endocrinology, Diabetes and Metabolism Department, Centro Hospitalar de São João, Porto, Portugal; 2Endocrinology Unit of the Pediatric Hospital, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; 3Pediatric Hospital - Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; 4Faculty of Medicine, University of Porto, Porto, Portugal; 5Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal.
Introduction: Type 1 diabetes (T1D) is an important endocrine disease in the pediatric age group. The shift from pediatrics to adult health care providers is a critical period for adolescents with diabetes.
Objective: Characterization of a pediatric population with T1D moved to adult health care between January/2001–April/2015.
Methods: Cross-sectional study with retrospective analysis of medical records.
Results: We evaluated 195 patients, 82 girls (42.1%) with a mean age of 7.94±3.40 years at diagnosis. Follow-up time was 9.50±3.50 years, with a mean number of visits of 30.60±11.40. At transition, the mean age was 17.96±0.93 years, with 10.03±3.56 years of disease. Mean BMI was 23.63±3.32 kg/m2 (SDS 0.74±1.01), with overweight in 57 (29.2%) and obesity in 8 patients (4.1%). Mean A1c in the last appointment was 8.7±1.6%; 47 patients (23.6%) had an A1c value <7.5% and 71 (36.4%) >9%. At transition time, 113 (57.9%) patients were treated with functional insulin therapy and 20 (10.3%) were on continuous subcutaneous insulin infusion (CSII). Insulin dose on last visit was 1.00±0.25 UI/kg. During follow-up, 184 (94.3%) patients reached the mean final height of 167.50±9.22 cm (SDS −0.47±1.09). Of these, only 6 (3.3%) did not reach the target height. It was found a decrease in mean height SDS on last appointment when compared with the first visit, in both sexes – male: 0.04±1.05 v. −0.54±0.96; P<0.001; female: 0.25±1.07 vs −0.46±1.22; P<0.001.
Conclusion: The age of T1D diagnosis is coincident with the age group with the highest incidence reported in the literature. Overweight found in 30% of patients may reflect the global trend towards weight gain. The recommended target of A1c was achieved by 23.6% of patients, despite 68.2% being on CSII and functional insulin therapy. Like other studies, the mean height SDS decreased during follow-up, suggesting an impaired growth, although there seems to be no impact on the final height.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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