Endocrine Abstracts

Status of carbohydrate metabolism in patients with hypercalcaemia and the influence of hypercalcemia on the risk of type 2 diabetes continue to be studied.

Objective: To study the prevalence of type 2 diabetes in patients with hypercalcemia and in patients without hypercalcemia.

Materials and methods: Continuous survey of 1000 people, average age 54.68±16.96 (727 women, 273 men) from 18 to 96 years. Examination: total calcium, total protein, creatinine, cholesterol and triglycerides with an analysis of morbidity (osteoporosis, kidney stones, cholelithiasis, ulcer disease, type 2 diabetes, hypertension, coronary heart disease, cardiovascular events, cancer, fractures in history).

Results: Hypercalcemia has been found in 26 people, mean age was 57.42±11.6 years. Type 2 diabetes is detected in 5 (19.2%) patients with hypercalcemia and 118 (12.1%) cases with type 2 diabetes were found among patients without hypercalcaemia.

Significant differences was detected in the prevalence of type 2 diabetes in patients with hypercalcemia and in patients without hypercalcemia (χ²=0.57, P<0.0001).

Conclusion: The results of the study show an increasing prevalence of type 2 diabetes in patients with hypercalcaemia. The results may indicate the influence of hypercalcemia in the frequency of manifestation of type 2 diabetes.