Endocrine Abstracts

Background: Obesity is associated with many diseases. e.g. cardiovascular diseases. The most common deficiency associated with obesity seems to be low concentrations of vitamin D that is associated with an increased risk of diabetes and other cardiovascular diseases. Low concentrations of vitamins are linked to accelerated atherosclerosis through increased oxidative stress. The purpose of this research was to investigate the association between obesity and vitamin B12(VB12), folic asid(FA) and vitamin D(VD) levels in patients.

Matherial-Method: The study was conducted at the outpatient clinic at Umraniye Research Hospital, between January and june 2015. We ennrolled 100 patients. Exclusion criteria included being a strict vegetarian, being over 50 or less than 18, current use of corticosteroids or vitamin supplements, long term use of proton pump inhibitors and intestinal absorbtion diseases. Blood was taken after a 8–12 hours overnight fasting and serum VB12, FA and VD levels are measured. BMI was calculated using the following formula: kg/height (m²). We found P<0.05 (statistical significance).

Results: Demographic details are in Table 1. There was no statistically significant correlation between BMI and VB12 or FA levels (P>0.05). Significant correlation exists between BMI and VD levels (P<0.05). There is no a significant relationship between age and VB12, FA and VD levels.

Conclusion: We compared VB12 status in patiens with obesity and can’t find any significant corelation. There is not enough research about FA levels in obesity but we found no correlation between obesity and serum FA levels. VD deficiency and secondary hyperparathyroidism are known to be prevalent in obesity and we find a significant correlation in our study.