ECE2016 Eposter Presentations Thyroid cancer (81 abstracts)
The increased coexistence of autoimmune thyroiditis (AIT) in children and adolescents with thyroid carcinoma (TC) in years 2001–2015 compared to years 1996–2000
Marek Niedziela 1, , Maciej Flader 1, , Jerzy Harasymczuk 2 , Ewa Trejster 3 , Danuta Breborowicz 4 , Barbara Rabska-Pietrzak 1, , Pawel Kurzawa 3, & Jan Breborowicz 4
1Department of Pediatric Endocrinology and Rheumatology, Poznan University of Medical Sciences, Poznan, Poland; 2Chair and Department of Pediatric Surgery, Traumatology and Urology, Poznan University of Mecal Sciences, Poznan, Poland; 3Division of Pathomorphology, Karol Jonscher’s Clinical Hospital, Poznan, Poland; 4Department of Tumor Pathology, Greater Poland Cancer Centre, Poznan, Poland; 5Chair and Department of Tumor Pathology, Poznan University of Medical Sciences, Poznan, Poland; 6Karol Jonscher’s Clinical Hospital, Poznan, Poland.
Introduction: In years 1996–2000, the predominance of papillary thyroid carcinoma (PTC) (70.3%) compared to follicular thyroid carcinoma (FTC; 27.0%) and medullary thyroid carcinoma (MTC; 2.7%) was observed in our region. AIT coexisted in 1 PTC (2.7% of all cancers and 3.8% in PTC group).
Aim: The aim of retrospective study was to analyze the coexistence of AIT and TC in years 2001-2015 in relation to years 1996–2000.
Material and methods: Patients aged <18 years with the histopathological diagnosis of TC were analyzed. AIT was confirmed by the presence of antithyroid antibodies in serum or based on cytological result obtained from biopsy.
Results: 47 TCs were confirmed in 2001–2015 (41 PTC, 1 FTC and 5 MTC) in 37 girls (78.7%) and 10 boys (22.3%). AIT coexisted only with PTC, in 4/13 (30.7%) 2001–2005, in 2/8 (25.0%) 2006–2010 and in 11/20 (55.0%) 2010–2015. The incidence of PTC/AIT coexistence in 2001–2015 was 41.4% (17/41), i.e. 10-fold more frequent than in 1996–2000.
Conclusions: High risk of the coexistence of PTC and AIT in years 2001–2015 suggests that the careful follow-up of patients with AIT is mandatory.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more