ECE2016 Eposter Presentations Thyroid (non-cancer) (120 abstracts)
Central/Peripheral vascularization and resistance index at Doppler ultrasound examination of thyroid nodules: are they useful to differentiate between benign and malignant pathology?
Néstor Pacenza , Melanie Rosmarin , Evelin Blan , Sol Serrano , Claudia Cejas , Noelia Sforza , Leonardo Serrano , Adriana Campero , Santiago Frid , María Cristina Faingold & Gabriela Brenta
Dr. Cesar Milstein Hospital, Buenos Aires, Argentina.
Thyroid Doppler ultrasound (TDUS) is highly used in the evaluation of thyroid nodules (TN). Malignant thyroid pathology has been more frequently associated with central vascularization of such nodules. There is controversy regarding the usefulness of the Resistance Index (RI) in the assessment of TN.
Our aim was to analyze the utility of vascularization characteristics and RI at TDUS in the distinction of benign and malignant TN.
Materials and methods: Characteristics of vascularization (peripheral or central and peripheral) and RI (estimated by blood flow speed at the prominent artery at TDUS) were analyzed in all patients who underwent thyroid surgery and had an US-guided fine needle aspiration biopsy (FNAB) performed in our institution from June 2011 to November 2015.
Results: Sixty two patients were included, 60 women and 2 men. Mean age was 68.2±6.8 years. Twenty two patients resulted in malignant (mostly papillary carcinoma) and 40 in benign pathology (mostly follicular adenomas and adenomatous nodules). Fifteen patients had 2 TN evaluated, leading to a total of 77 nodules (50 benign and 27 malignant).
We found no significant difference between RI of benign and malignant nodules: 0.59±0.09 vs. 0.60±0.10 respectively.
Thirty one TN showed peripheral vascularization (PV) exclusively: 20 were benign (64.5%) and 11 malignant (35.5%). Fourty six exhibited central and peripheral vascularization (C/PV): 30 were benign (65.2%) and 16 malignant (34.8%). There was not statistically significant difference between both. Sensitivity for C/PV for malignant pathology was 34.8% and specificity was 64.5%.
Conclusion: In our experience, characteristics of vascularization (peripheral or central and peripheral) and the RI of TN at TDUS alone were not useful to distinguish between benign and malignant pathology in our population.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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