ECE2016 Guided Posters Obesity (10 abstracts)
Ventilatory anaerobic threshold six months after RYGB
Snezana Polovina 1, , Ivana Nedeljekovic 2, , Djordje Bajec 3, , Mirjana Sumarac-Dumanovic 1, , Dejan Radenkovic 3, , Aleksandra Kendereški 1, , Pavle Gregoric 4, , Goran Cvijovic 1, , Dusan Micic 4 , Svetlana Zoric 1 , Danica Stamenkovic-Pejkovic 1 , Jelena Milin-Lazovic 5 , Danka Jeremic 1 , Ana Gligic 1 & Dragan Micic 5
1Clinic for Endocrinology, Diabetes and Diseases of Metabolism, Clinical Center of Serbia, Belgrade, Serbia; 2Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia; 3Clinic for Digestive Surgery, Clinical Center of Serbia, Belgrade, Serbia; 4Emergency Center, Clinical Center of Serbia, Belgrade, Serbia; 5Medical Faculty, University of Belgrade, Belgrade, Serbia.
Introduction: Obesity is associated with high risk for coronary artery disease, high blood pressure, elevated serum cholesterol level, malignancy and Type 2 diabetes mellitus. After weight loss, especially after bariatric surgery there is improvement in blood pressure, metabolic parameters and ventilatory anaerobic threshold.
Material and methods: Ergospirometry (Shiller CS-200, Bruce protocol) was performed in 50 obese patients before and six months after R en Y gastric bypass. Baseline characteristics were: BMI 43.8 kg/m2, 43±12.7 years of age (female n=37, male n=13). Changes in pulse rate, systolic blood pressure (SBP) in rest and maximal SBP, diastolic blood pressure in rest (DBP) and maximal DBP, ventilatory anaerobic threshold (VAT/VO2) and peak in oxygen consumption (VO2) were analyzed. Baseline VO2 less than 14 ml/kg per min was exclusion criteria for bariatric surgery.
Results: Change in pulse rate (98.7±12.2 vs 88.01±13.46/min) was significant (P<0.0001). SBP in rest decreased (135±14 vs 131±13 mmHg) with significance P=0.017. Max SBP decreased with high significance (181±26 vs 162±22 mmHg; P<0.0001). DBP in rest also decreased (85±8 vs 80±9 mmHg; P<0.0001) and max DBP decreased from 98±12 to 92±10 mmHg (P=0.002). There was improvement in VAT/VO2 (17.8±3.44 vs 20.86±4.70 ml/kg per min; P<0.0001) and in peak of oxygen consumption, VO2 (20.79±3.63 vs4.97±4.37 ml/kg per min; P<0.0001).
Conclusion: Our results suggest that bariatric surgery could improve cardiorespiratory fitness. Ventilatory anaerobic threshold, oxygen consumption, pulse rate, maximal systolic and diastolic blood pressure as well as systolic and diastolic blood pressure in rest were improved six months after RYGB.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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