ECE2016 Eposter Presentations Thyroid (non-cancer) (120 abstracts)
Evaluation of ovarian reserve in terms of ovarian volume, antral follicule count and hormonal tests in Hashimoto’s thyroiditis
Turkan Mete 1 , Aysu Basak Ozbalci 2 , Elif Kilic Kan 1 , Gulhan Duman 1 , Halise Cinar Yavuz 3 , Gultekin Ozan Kucuk 4 , Ismail Ozer 5 , Hacer Pinar Ozturk Kurt 6 & Aysegul Atmaca 7
1Ministry of Health, Samsun Training and Research Hospital Department of Endocrinology and Metabolism, Samsun, Turkey; 2Ministry of Health, Samsun Training and Research Hospital Department Of Radiology, Samsun, Turkey; 3Turgut Ozal University, School of Medicine Department of Endocrinology and Metabolism, Ankara, Turkey; 4Ministry of Health, Samsun Training and Research Hospital Department Of General Surgery, Samsun, Turkey; 5Ministry of Health, Samsun Training and Research Hospital Department Of Nephrology, Samsun, Turkey; 6Ministry of Health, Samsun Training and Research Hospital Department Of Internal Medicine, Samsun, Turkey; 7School of Medicine, Ondokuz Mayis University Department of Endocrinology and Metabolism, Samsun, Turkey.
Introduction: Our aim is to investigate whether ovarian reserve is decreased in patients with euthyroid Hashimoto’s thyroiditis (HT).
Method: Our study included 110 euthyroid HT patients and 72 age matched healthy women (controls; C). In all patients FSH, LH E2, and P levels were measured from blood samples, and ovarian volumes (OV) and antral follicule count (AFC) were measured using ultrasonography at 3rd day of menstruation.
Results: No statistically significant difference was detected in FSH, LH, E2 and P levels between groups (P value respectively; 0.117, 0.420, 0.941, 0.644). Total ovarian volumes were not statistically different between groups (P=0.165). Total AFC were significantly lower in the HT group than the controls (P<0.001). Total AFC were strongly and negatively correlated with AntiTPO (r=−0.215, P=0.004) and AntiTg (r=−0.251, P=0.001).
Conclusion: Our study shows decreased ovarian reserve in HT patients than healthy controls even in euthyroid state.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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