ECE2016 Eposter Presentations Thyroid (non-cancer) (120 abstracts)
Assessment of thyroid function during the three trimesters of pregnancy in alexandria region (Egypt)
F E Amara 1 , M H Megalaa 1 , Y I Oraif 2 , M G Moawad 1 , M A Korani 3 , M F Amara 1 & S El-Sheikh 1
1Department of Internal Medicine, Alexandria University, Alexandria, Egypt; 2Department of Gynaecology and Obstetrics, Alexandria University, Alexandria, Egypt; 3Department of Internal Medicine, Menofia University, Alexandria, Egypt.
Introduction: Pregnancy is associated with significant reversible changes in thyroid functions due to certain hormonal changes e.g. HCG and estrogen.
Objective: To study thyroid functions in different trimesters of pregnancy compared to control age matched non pregnant women.
Design and Methods: Cross sectional study of 90 pregnant women divided into three groups in the three trimesters of pregnancy compared to 30 ages matched non-pregnant women. Study of FT3, FT4, TSH and TPO using COBAS analyser.
Results: In general, our study showed significant differences between pregnant and non-pregnant women regarding FT4 and TSH but not FT3 and antiTPO. Thyroid function abnormalities were increased with advance in pregnancy.
Conclusion: The discrepancy between FT4 and TSH in pregnancy is mostly due to presence of many stimulatory and inhibitory factors. Screening of FT4, TSH, HCG and TPO is important during pregnancy.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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