ECE2016 Eposter Presentations Endocrine tumours and neoplasia (68 abstracts)
The contribution of fast test in the diagnostic approach of hypoglycemia in non-diabetic patients
Radhouen Gharbi , Fatma Chaker , Melika Chihaoui , Syrine Danguir , Mariem Yazidi , Ons Rejeb & Hedia Slimane
Faculty of medecine, Tunis, Tunisia.
Introduction: Hypoglycemia is an uncommon complaint among non diabetic patients. The aim of this study was to determine the role of fast test in the diagnostic approach to hypoglycemia.
Patients and methods: It was a retrospective study, including 40 patients admitted in the endocrinology department from 2001 to 2015 for hypoglycemia signs. We collected clinical and biologic data, fast test results and final diagnosis of hypoglycemia.
Results: The mean age was 46 years [±19.1]. 57.5% of the patients were women. The mean duration of symptoms was 33 weeks [±55]. Sixty five percent had neuroglycopenic signs. The mean capillary blood glucose was 0.38 g/l [±0.15]. Two patients had adrenal insufficiency, and 3 had sulfamid induced hypoglycemia. Supervised fast test was undertaken in 20 patients. In 2 patients hypoglycemia occurred in the first 24 h, and final diagnosis was insulinoma in both cases. In 3 patients fast test was stopped because of non hypoglycemic symptoms, and 5 patients stopped voluntarily the test. five hours glucose tolerance test was performed in 25 patients: Reactive hypoglycemia was diagnosed in 77.5%; 68% had glucose tolerance abnormalities.
Conclusion: Insulinoma was diagnosed in 5% of the patients admitted for hypoglycemia. The two cases was identified by a hypoglycemia occurring during the first day fast test. To confirm organic hypoglycemia, fast test is a chief pattern but other investigations are often necessary.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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