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Endocrine Abstracts (2016) 41 EP471 | DOI: 10.1530/endoabs.41.EP471

1Laboratory of Endocrinology and Metabolism, Algiers, Algeria; 2IBN Ziri Bologhine Hospital, Algiers, Algeria.


Introduction: Obesity and especially abdominal obesity is therefore often associated with atherogenic dyslipidemia which lead to cardiovascular complications.

The aim of our study was to analyze the distribution of cholesterol and triglycerids and to determine the prevalence of dyslipidemia in the Algerian adult population and their variation depending on the presence or absence of obesity.

Methodology: Capillary samples using a validated lipids player (Accutrend GCT) were performed in 2210 individuals randomly selected from the general population. High cholesterol is defined by a fasting cholesterol (fasting 12 h)>2 g/l. The hypertriglyceridemia is defined by a triglyceride levels after 12 h of fasting >1.5 g/l, or a person treated to dyslipidemia.

Results: The mean fasting total cholesterol in our sample was 1.70 g/l (1–2.4).

The Average fasting triglycerids is 1.15 g/l (0.39–2.69). A known history of dyslipidemia was rated at 7.06% of subjects. A Dyslipidemia was detected in 26.11% of the individuals in our population.

The Comparison of the obese group with the non-obese group found a clear predominance of the prevalence in known and screened dyslipidemia in the obese group (global obesity and android) especially in men.

In multi-analysis varied patients with known and screened dyslipidemia are more obese than the normolipidemic OR1 known 2.4 (95% CI 1.59–3.63) P<0.001. OR2 screened 1.63 (95% CI 1.27–2.08) P<0.001. When we analyzed abdominal obesity (IDF) known and screened dyslipidemic subjects are also more obese than subjects with normal lipid profile. Known OR1 2.27 (95% CI 1.24–4.15) P<0.001. OR2 screened1.8 (95% CI 1.38–2.62) P<0.001.

Conclusion: Dyslipidemia is a frequent complication of obesity that must be screened to prevent installatation of cardiovascular complications that often have implications for high morbidity and mortality and a significant financial cost.

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