Endocrine Abstracts

Introduction: We aimed to investigate the homeostasis model assessment of insulin resistance (HOMA-IR) and relation of HOMA-IR with age, sex and body mass index (BMI) and the prevalence of diabetes in Turkish population of different regions.

Methods: Cross-sectional observational study was done in the frame of Turkish prevalence of insulin resistance multicenter study. The study sample consisted of volunteers from seven different regions of Turkey. Weight, height, waist circumference were determined. BMI, blood pressure, fasting blood glucose, fasting blood insulin was performed. Insulin resistance was calculated using HOMA-IR.

Results: The prevalence of DM, impaired fasting glucose and insulin resistance (IR) were, 11.1, 21.3, 26.2% respectively in seven regions of Turkey. IR was detected 28.9% in women, 25.1% in men. The difference between men and women were significant (P=0.04). The prevalence of IR in postmenopausal women (30.8%) was higher than premenopausal (25.1%) (P<0.04). According to age groups; prevalence of IR in the age of 50–59 (33.8% P<.001) was higher than the other age groups. The prevalence of IR was higher in BMI>25, in subjects with hypertension and in subjects with living in city center (P<.05).

Conclusion: The high prevalence of IR and DM in Turkey is one of the important public health problem. There is an urgent necessity to institute more aggressive nation wide public health measures and screening programs about obesity.