Endocrine Abstracts

Pituitary gigantism occurs due to hypersecretion of GH and insulin-like growth factor-1 (IGF-1) in children and adolescents before the closure of epiphyseal growth plates. This hormonal disorder is usually due to an adenoma or hyperplasia of the anterior pituitary gland and like other tumoral conditions in children often has a genetic background. Recently we demonstrated that a genetic predisposition is present in just under half of cases of pituitary gigantism. The best recog...

Prof. Adrian Daly MB BCh, PhD, was born in Boston, Massachusetts and raised in the United States and Ireland. He received an Honors Bachelor of Science degree in Physiology from University College Dublin, Ireland in 1991 and his medical degree (MB BCh BAO) from the Royal College of Surgeons in Ireland Medical School in 1996. After undertaking postgraduate medical training, he received an MSc in Mole...