ECE2015 Eposter Presentations Thyroid (non-cancer) (160 abstracts)
Two cases with primary thyroid lymphoma developed on the basis of Hashimoto's thyroiditis
Hande Peynirci 1 , Pinar Sisman 1 , Cigdem Aksu 2 , Ozen Oz Gul 1 , Soner Cander 3 , Erdinc Erturk 1 & Canan Ersoy 1
1Department of Endocrinology and Metabolism, Uludag University Medical School, Bursa, Turkey; 2Department of Internal Medicine, Uludag University Medical School, Bursa, Turkey; 3Department of Endocrinology and Metabolism, Sevket Yilmaz Training and Research Hospital, Bursa, Turkey.
Introduction: Primary thyroid lymphomas are rare cancers and account 1–5% of all thyroid cancers and 3% of all extranodal non hodgkin lymphomas (NHLs). We aimed to present cases of thyroid lymphoma encountered in our clinic.
Case 1: A 54-year-old female patient admitted with pain and swallow on the cervical region. In ultrasonographic (USG) thyroid examination, it was found that both thyroid lobes were very large with routh parenchyme consistent with chronic thyroiditis; also there was a solid nodule 23 mm in diameter in left side. In fine-needle aspiration biopsy (FNAB) of thyroid, there were suspicious findings strongly indicating lymphoid hyperplasy. Patient underwent total thyroidectomy. Pathology results were consistent with extranodal (MALT type) marginal zone lymphoma. There were no pathologic findings implicating systemic involvement; patient is still followed-up.
Case 2: A 40-year-old female patient admitted with hypothyroidism. In USG examination of thyroid, it was found that thyroid parenchyme was extensively heterogeneous and there were multiple nodules. FNAB findings were reported as Hashimoto’s thyroiditis and papillary carcinoma. Patient underwent total thyroidectomy and pathology results were considered as morphologic and immunephenotypic findings consistent with extranodal (MALT type) marginal zone lymphoma. Patient underwent radiotherapy. She is in remission and still followed-up.
Discussion: Primary thyroid lymphomas are rare cancers. Hashimoto’s thyroiditis has been found 94% of the primary thyroid lymphoma cases. MALT lymphoma of thyroid has best prognosis with 100% of 5-year survival expectancy. Early diagnosis is important.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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