ECE2015 Eposter Presentations Thyroid (non-cancer) (160 abstracts)
Elevated neutrophil/lymphocyte ratio in patients receiving any replacement therapy with euthyroid Hashimoto
Havva Keskin 1 , Yasemin Kaya 4 , Kenan Cadirci 2 , Cuneyt Kucur 5 , Elif Ziypak 2 , Eda Simsek 2 , Hakan Gozcu 2 , Senay Arikan 3 & Ayse Carlioglu 2
1Medeniyet University, Istanbul, Turkey; 2Erzurum Training and Research Hospital, Erzurum, Turkey; 3Kirikkale University, Kirikkale, Turkey; 4Ordu University, Ordu, Turkey; 5Dumlupinar University, Kutahya, Turkey.
Introduction: Neutrophil lymphocyte rate (NLO), which is obtained from peripheric blood and used as mathematical rates of lymphocyte numbers, is accepted as available and practical indicator of systemic inflammation existence. We aimed to search NLO between Hashimoto’s thyroids patients who have autoimmune thyroid and also include an aetiopathogenesis auto-inflammatory process, and healthy control group with this study.
Method: 59 patients who have been diagnosed as Hashimoto’s thyroiditis, euthyroid and receive any treatment, 53 people who have no in point of age, BMI among them, totally 112 people have been incorporated to the study. The average age of patients has been counted as 33.8±12.8 years and the average age of control group has been counted as 30.1±12.4 years. Statistically significant difference couldn’t be determined (P=0.1).
Results: As a result of this study; patient group NLO has been founded as 4.0±0.7 and healthy group NLO has been founded as 2.0±0.1. Statistically significant difference has been determined (P=0.01). While statistically significant difference hasn’t been determined between healthy group and patient group in point of white blood cell count (7.9±0.3 and 7.4±0.2, P=0.1) among neutrophil (5.5±0.3 and 5.4±1.1, P=0.9), the difference has been determined in point of lymphocyte values (2.04±0.1 and 3.1±0.5, P=0.05). Positive correlation has been determined between NLO and CRP (r=0.6, P<0.0001), thyroid peroxidase immune body level and (r=0.3, P<0.001), anti-thyroglobulin immune body level and (r=0.3, P=0.006), white blood cell count and (r=0.4, P<0.001) and also between neutrophil level and NLO (r=0.265, P=0.007), neutrophil and lymphocyte count (r=0.776, P<0.001).
Discussion: Present symptoms show that NLO values have statistically significant increased in euthyroid Hashimoto’s thyroiditis in comparison with healthy control group and it is seen that it correlated with autoantibody level which is used for the diagnosis of disease. In these results, we think that systemic inflammatory process is important in Hashimoto’s thyroiditis aetiology.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more