ECE2015 Eposter Presentations Thyroid cancer (90 abstracts)
Thyroid malignancy risk of incidental thyroid nodules in patients with non-thyroid cancer
Mehmet Yalcin 1 , Alev Altinova 1 , Cigdem Ozkan 1 , Fusun Balos Toruner 1 , Mujde Akturk 1 , Ozgur Akdemir 2 , Tugce Emiroglu 3 , Derda Gokce 3 , Aylar Poyraz 4 , Ferit Taneri 5 & Ilhan Yetkin 1
1Department of Endocrinology and Metabolism, Faculty of Medicine, Gazi University, Ankara, Turkey; 2Department of Nuclear Medicine, Faculty of Medicine, Gazi University, Ankara, Turkey; 3Department of Internal Medicine, Faculty of Medicine, Gazi University, Ankara, Turkey; 4Department of Pathology, Faculty of Medicine, Gazi University, Ankara, Turkey; 5Department of General Surgery, Faculty of Medicine, Gazi University, Ankara, Turkey.
Objective: Thyroid incidentaloma is a common endocrinological disorder. Current literature regarding the risk of thyroid cancer in incidentalomas found in patients with non-thyroid cancer is limited. The aim of the present study was to investigate the frequency of thyroid malignancy in thyroid incidentalomas detected in patients with non-thyroid cancer.
Methods: The database of 287 thyroid nodules from 161 patients with a history of non-thyroid cancer followed between 2008 and 2014 were retrospectively evaluated.
Results: From 287 thyroid nodules, 69.7% had a benign final cytology. Thyroid cancer detected in one nodüle while follicular neoplasia detected in four nodules, atypia of unknown significance (AUS) detected in ten nodules, hurthle cell neoplasia detected in five nodules and suspicious for malignancy detected in six nodules according to fine needle aspiration biopsy results. Metastasis of the non-thyroid cancer to the thyroid gland were detected in four nodules. Twenty seven nodules from 15 patients were removed with surgery. There were three malignant nodules found after surgery (one papillary, one follicular and one medullary cancer). In addition to these three thyroid cancers, two patients with benign nodules had co-incidental thyroid cancer detected after surgery. Finally, 11.1% of thyroid nodules which underwent thyroid surgery had malignant histopathology except co-incidental and metastatic cancers.
Conclusion: The frequency of thyroid malignancy seems not to be substantially increased in incidental thyroid nodules detected in patients with non-thyroid cancer when these patients were evaluated in nodule-based approach.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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