ECE2015 Eposter Presentations Thyroid cancer (90 abstracts)
Histopathology results of follicular neoplasia according to Bethesda classification in thyroid fine-needle aspiration biopsy
Sevilay Ozmen 1 , Ilknur Calik 1 , Ebru Sener 1 , Ozge Timur 2 , Ayse Carlioglu 3 , Hakan Sevimli 2 , Senay Arikan Durmaz 3 & Ali Kurt 1
1Department of Pathology, Training and Research Hospital, Erzurum, Turkey; 2Department of Internal Medicine, Training and Research Hospital, Erzurum, Turkey; 3Department of Endocrinology, Training and Research Hospital, Erzurum, Turkey.
Introduction and aim: Interpretation of follicular neoplasia classification according to Bethesda system in thyroid fine needle aspiration biopsy is very different among pathologist. A number of definition including ‘follicular lesion’, ‘follicular proliferation’, ‘follicular lesion of undetermined significance’, and ‘follicular neoplasia’ were used in terminology. A clearly discrimination between nodular goitre, follicular adenoma, and follicular carcinoma cannot lack due to same cytomorphologic features. Approximately 15–30% of case of follicular neoplasia in thyroid fine-needle aspiration biopsy (FNA) is considered as malignity. Aim of this study is to confirm with histopathological diagnosis after thyroidectomy in patients with follicular neoplasia according to Bethesda classification.
Materials and methods: Results of FNA in totally 402 patients with nodular goitre were achieved from our hospital records from 2012 to 2014 years. All the patients had undergone totally or subtotal thyroidectomy. We retrospectively re-evaluated postoperatively biopsy results.
Results: We described ten patients whom diagnosis of FNA were follicular neoplasia but results of postoperative biopsy were found adenomatous nodule (n=1), ‘adenomatous nodule and chronic lenfocytic thyroiditis’ (n=1), ‘papillary carcinoma’, ‘follicular variant (n=2)’, ‘nodulary goitre’ (n=4), ‘adenomatous nodule-Hürthle cell variant (n=1)’, and ‘well-differentiated follicular neoplasia’.
Conclusions: Our finding demonstrated that descriptive criteria of folliculary neoplasia in FNA substantially point out hyperplastic proliferation rather than neoplasia.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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