ECE2015 Eposter Presentations Pituitary: clinical (121 abstracts)
Acquired male hypogonadotropic hypogonadism in a type 2 diabetes patient revealing empty sella
Hela Marmouch 1, , Tasnim Slim 1 , Fadia Boubaker 1 , Sondes Arfa 1 , Sameh Graja 1, , Hanene Sayadi 1, , Manel Jmal 1, & Ines Khochtali 1,
1Department of Internal Medicine–Endocrinology, Monastir, Tunisia; 2Faculty of Medicine, Monastir, Tunisia.
Introduction: Empty sella in male patients is a very rare situation. It could be diagnosis in acquired male hypogonadotropic hypogonadism or hypopituitarism.
Case report: A 55-year-old type 2 diabetes male was referred to our hospital with erectile dysfunction (ED). He has three children. His secondary sex characteristics, sexual function, and ejaculation were previously normal but for the last 3 years he had ED. His genital stage was Tanner V, and pubic hair stage was Tanner III. There were no varicoceles. The diabetes was poorly controlled (Hb1Ac=9%). His hormonal data were LH 1.1 mIU/ml (normal: 2–8 mIU/ml), FSH 1.8 mIU/ml (2–12 mIU/ml), testosterone 1.2 ng/ml (3–7 ng/ml), and FT4 13 pmol/l (10–20 pmol/l). The rate of PSA was normal. Magnetic resonance imaging of the head revealed slight depression of the diaphragma sellae, indicating an ‘empty sella’. We diagnosed acquired hypogonadtropic hypogonadism related empty sella. A replacement androgen therapy was introduced. Twelve months after hormone replacement therapy, the ED wasn’t disappear but the quality of life of this patient was better.
Discussion: ED is common in type 2 diabetes men poorly controlled. It may reveal endocrine dysfunction such as acquired functional male hypogonadotropic hypogonadism (MHH). Pituitary MRI is frequently normal.
Conclusion: In this observation, we report a common situation in type 2 diabetes patient which revealed a rare case of acquired MHH due to empty sella. Pituitary MRI is interesting in acquired MHH and can reveal multiples others endocrine deficiency.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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