Prevalence of metabolic syndrome among human immunodeficiency virus and hepatitis C subjects in Southern Brazil

Maristela Beck; Helen  Cezimbra; Fabio  Pedro; Francisco Galarreta; Luiz Felipe Barin

doi:10.1530/endoabs.37.EP649

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Endocrine Abstracts (2015) 37 EP649 | DOI: 10.1530/endoabs.37.EP649

ECE2015 Eposter Presentations Obesity and cardiovascular endocrinology (108 abstracts)

Prevalence of metabolic syndrome among human immunodeficiency virus and hepatitis C subjects in Southern Brazil

Maristela Beck , Helen Cezimbra Cezimbra , Fábio Pedro Pedro , Francisco Galarreta & Luiz Felipe Barin

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Federal University of Santa Maria, Santa Maria, Brazil.

Objective: To investigate the metabolic syndrome and dyslipidemia prevalence among human immunodeficiency virus (HIV) and hepatitis C (HCV) subjects in Southern Brazil.

Methods: Cross-sectional study, including 127 subjects (n=59 HIV positive only, n=36 HIV/HCV positive, and n=32 HCV positive only) were accessed for HOMA index, metabolic syndrome, and dyslipidaemias.

Results: In HIV group there were 27% metabolic syndrome by IDF criteria and 26% by HOMA2-IR index (1.4 cut-off), 63% larger waist by IDF criteria and 26% abdominal obesity. To HIV/HCV coinfection group there were 30% metabolic syndrome by IDF, but 54% by HOMA2-IR index, 42% larger waist, but 52% abdominal obesity. To HCV group there were 25% metabolic syndrome by IDF and 38% by HOMA2-IR index, 67% larger waist, and 47% abdominal obesity.

Conclusions: The presence of HCV coinfection is responsible for alarming levels of insulin resistance, associated with a more favorable lipid profile that could act as a confounder in the clinical diagnosis of metabolic syndrome.