ECE2015 Eposter Presentations Obesity and cardiovascular endocrinology (108 abstracts)
Effects of an 8-week supervised, structured lifestyle modification programme on anthropometric, metabolic, and cardiovascular risk factors in severely obese adults
Catherine Crowe 1 , Irene Gibson 2 , Katie Cunningham 1, , Claire Kerins 2 , Caroline Costello 2 , Jane Windle 2 , Paula O’Shea 3 , Mary Hynes 1, , Brian McGuire 1, , Katriona Kilkelly 1 , Helena Griffin 1 , Timothy O’Brien 1 , Jenni Jones 2, & Francis Finucane 1,
1Bariatric Medicine Service, Galway Diabetes Research Centre, HRB Clinical Research Facility, Galway, Ireland; 2Croi, The West of Ireland Cardiac Foundation, Heart and Stroke Centre, Moyola Lane, Newcastle, Galway, Ireland; 3Department of Clinical Biochemistry, Galway University Hospitals, Galway, Ireland; 4School of Psychology, National University of Ireland, Galway, Ireland; 5Discipline of Health Promotion, National Institute of Preventive Cardiology, National University of Ireland, Galway, Ireland.
Background: Lifestyle modification is fundamental to obesity treatment, but few studies have described the effects of structured lifestyle programmes specifically in bariatric patients. We sought to describe changes in anthropometric and metabolic characteristics in a cohort of bariatric patients after participation in a nurse-led, structured lifestyle programme.
Methods: We conducted a retrospective, observational cohort study of adults with a BMI ≧40 kg/m2 (or ≧35 kg/m2 with significant co-morbidity) who were attending a regional bariatric service and who completed a single centre, 8-week, nurse-led multidisciplinary lifestyle modification programme. Weight, height, waist circumference, blood pressure, HbA1c, fasting glucose and lipid profiles, functional capacity (Incremental Shuttle Walk Test) and anxiety, and depression scores before and after the programme were compared in per-protocol analyses.
Results: Of 183 bariatric patients enrolled, 150 (81.9%) completed the programme. Mean age of completers was 47.9±11.2 years. 34.7% were males. There were statistically significant reductions in weight (129.6±25.9 kg vs 126.9±26.1 kg, P<0.001), BMI (46.3±8.3 kg/m2 vs 44.9±9.0 kg/m2, P<0.001), waist circumference (133.0±17.1 cm vs 129.3±17.5 cm in women and 143.8±19.0 cm vs 135.1±17.9 cm in men, both P<0.001) as well as anxiety and depression scores, total- and LDL-cholesterol and triglyceride levels, with an increase in functional capacity (5.9±1.7 vs 6.8±2.1 METS, P<0.001) in completers at the end of the programme compared to the start. Blood pressure improved, with reductions in systolic and diastolic blood pressure from 135±16.2 to 131.6±17.1 (P=0.009) and 84.7±10.2 to 81.4±10.9 mmHg (P<0.001) respectively. The proportion of patients achieving target blood pressure increased from 50.3 to 59.3% (P=0.04). The proportion of patients with diabetes achieving HbA1c <53 mmol/mol increased from 28.6 to 42.9%, P=0.02.
Conclusions: Bariatric patients completing an eight week, nurse-led structured lifestyle programme had improved adiposity, fitness, lipid profiles, psychosocial health, blood pressure, and glycaemia. Further assessment of this programme in a pragmatic randomised controlled trial seems warranted.
Disclosure: The work was supported by a project grant from the Health Service Executive, Ireland.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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