ECE2015 Eposter Presentations Obesity and cardiovascular endocrinology (108 abstracts)
Cardiovascular disease in patients with primary hyperparathyroidism
Elena Brutskaya-Stempkovskaya 1 , Alla Shepelkevich 1 , Natalya Rekechinskaya 2 , Tatyana Leonova 2 & Tatyana Churay 3
1Belarusian State Medical University, Minsk, Belarus; 2Minsk Cancer Center, Minsk, Belarus; 3Minsk Endocrinology Center, Minsk, Belarus.
Introduction: Patients with primary hyperparathyroidism (PHPT) have an increased cardiovascular risk. However, the data on the relationship severity of PHPT clinical forms and prevalence of cardiovascular disorders are controversial.
Objective: Studying cardiovascular disease in patients with manifested forms of PHPT compared with mild forms.
Materials and methods: We studied 136 patients with PHPT (assesses arrhythmias, hypertension, coronary disease), a general medical examination were made. The indicators calcium and phosphorus metabolism (PTH, vitamin D, Ca general, Ca++, phosphates) were investigated.
Results: The mild PHPT were diagnosed in 54 patients with a mean age of patients was 51.5±11.6 years, manifested forms PHPT were diagnosed in 82 patients, the average age of the patients was 52±10.4 years. Cardiovascular disease were found in 19 (35.1%) patients with mild forms of PHPT and 38 (45.2%) with the manifested PHPT. A strong statistically significant correlation between the severity of clinical manifestations PHPT and incidence of cardiovascular disease in patients with PHPT (R=0.81, P<0.05).
Conclusion: These results suggest the high incidence of cardiovascular disease in patients with manifested PHPT and the low diagnostic rate of mild forms of PHPT.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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