Endocrine Abstracts

Introduction: Currently, there are few data on long-term effects of bariatric surgery. We present the results of 5-year follow-up of a cohort of patients with gastric bypass surgery (GBP).

Objectives: i) To determine the prevalence of major comorbidities of morbid obese; ii) to evaluate the gastric bypass effect on this comorbidities, and 10-year estimated cardiovascular risk after 5-year follow-up; and iii) to assess the impact of bariatric surgery on the quality of life in these patients.

Methods: Prospective analysis in a cohort of 124 patients with morbid obesity who underwent bypass surgery. Demographic and anthropometric parameters, 10-year risk for coronary heart disease (estimated by Framingham risk score), complications from surgery and quality of life through Bariatric Analysis and Reporting Outcome System (BAROS) test were analysed before surgery and during follow-up.

Results: A total of 124 patients, who underwent surgery between 2005 and 2009, where included. The mean age was 37.88±10.29 years, 76.6% were women and the mean preoperative BMI was 51.71±7.35 kg/m². At 2 and 5 years of follow-up, remains a BMI of 30.48±4.7 and 31.27±7.08 kg/m² respectively. After 5 years of follow up, the percentage of weight lost was 68.31%. Remission of hypertension, dyslipidemia, and diabetes mellitus type 2 had occurred in 89.5, 95.8, and 95.7% respectively (P<0.001). The Framingham risk score was reduced from 7.7±9.5 to 2.8±3.5% (P<0.005). Regarding surgical complications, 14.7% showed early complications and 29% late complications. BAROS test was successful in 95% of cases.

Conclusions: In our area, outcomes from gastric bypass in obtaining weight lost and resolution of comorbidities after 2 years of surgery also remains at 5-year follow up with a minimum rate of surgical complications.