Endocrine Abstracts

Aims: The metabolic syndrome (MetS) is a summary measure of important CVD risk factors that frequently coexist. The syndrome is evident in 20–30% of middle-aged women and has been linked to the development of CVD and diabetes. The aim of the study was to examine the differences in demographic and clinical profiles among older (≥60 years) and younger (<60 years) patients with MetS.

Methods: The study was included 45 older (mean age 63.1±12.1 years, 25 females and 20 males) and 40 younger (mean age 42.3±9.9 years, 30 females and ten males) patients wih MetS. MetS was defined as in ATP III. Demographic and biochemical parameters were compared between groups. Insulin resistance (IR) was estimated using the homeostasis model assessment (HOMA).

Results: Among older patients, 11.9% were smokers and 9.1% informed alcohol consumption. However, 29.5% of younger patients were smokers and only 12.1% of them consumed alcohol (P=0.05 and P=0.30). Mean levels of waist circumference, systolic, diastolic blood pressures, triglyceride, and LDL-cholesterol were statistically significantly higher than those of younger patients with MetS (P=0.001, P=0.01, P=0.001, P=0.02, and P=0.002 respectively). Mean levels of HOMA-IR were found to be 2.3±0.9 in young and 2.7±0.02 in elderly group.

Conclusions: There are differences between older and young patients with metabolic syndrome for waist circumference, smoking, blood pressures, and lipid levels.