ECE2015 Eposter Presentations Obesity and cardiovascular endocrinology (108 abstracts)
The effect of the type of the bariatric surgery in the lipid profile: an age, sex, BMI, and excess weight loss matched study
Filipe Cunha 1, , Joana Oliveira 1, , John Preto 3 , Ana Saavedra 1, , Maria Costa 1, , Daniela Magalhães 1 , Rita Bettencourt-Silva 1 , Paula Freitas 1, , Ana Varela 1, & Davide Carvalho 1,
1Serviço Endocrinologia, Diabetes e Metabolismo do Centro Hospitalar São João, Porto, Portugal; 2Faculdade de Medicina da Universidade do Porto, Porto, Portugal; 3Serviço de Cirurgia Geral do Centro Hospitalar São João, Porto, Portugal.
Introduction: Bariatric surgery improves lipid profile. A still unanswered question is whether this improvement is merely weight dependent or also results from factors inherent to specificities of the bariatric procedure itself. We aimed to study lipid profile 1 year after bariatric surgery and compare its changes between the different procedures in patients matched for initial weight and for weight loss.
Methods: We retrospectively analysed patients submitted Roux-en-Y gastric bypass (RYGB), adjustable gastric banding (AGB), or sleeve gastrectomy (SG) between 2010 and 2013. Patients were matched for age (±5years), sex, pre-surgery BMI (±2 kg/m2), and EWL (±5%). Baseline and 1-year lipid profile, its variation and percentage of variation was compared between surgeries.
Results: We analysed 229 patients: 72 pairs RYGB-AGB; 47 pairs RYGB-SG; and 33 pairs AGB-SG. The median age was 41 (35–52) years and 11.8% were males. BMI at the time of surgery was 44.0±4.6 and 32.1±4.4 kg/m2 at 1 year. EWL at 1 year was 64.2±18.9%. There were no differences in baseline lipid profile between patients submitted to different types of bariatric surgery. At 1 year, HDL and TG improved similarly with all surgeries. TC and LDL at 1 year decreased significantly more in patients submitted to RYGB than in weight-matched patients undergoing AGB or SG.
Conclusions: RYGB is the only bariatric surgery that reduces TC and LDL in age-, sex-, BMI-, and EWL-matched patients. All three procedures improved TG and HDL similarly when the confounding effect of weight loss is eliminated.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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