ECE2015 Eposter Presentations Diabetes (complications & therapy) (143 abstracts)
Diabetes mellitus and chronic kidney disease: two decades of consultation of diabetes and kidney transplant, a retrospective study
Ana Margarida Balsa 1 , Margarida Bastos 2 , Rosa Dantas 1 , Carla Batista 2 , Rui Alves 3 , António Roseiro 3 , Carolina Moreno 2 , Daniela Guelho 2 , Luís Cardoso 2 , Nuno Vicente 2 , Diana Martins 2 , Diana Oliveira 2 , Márcia Alves 1 , Joana Guimarães 1 , Alfredo Mota 4 & Francisco Carrilho 2
1Serviço de Endocrinologia, Diabetes e Nutrição do Centro Hospitalar do Baixo Vouga, Aveiro, Portugal; 2Serviço de Endocrinologia, Diabetes e Metabolismo do Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; 3Serviço de Nefrologia do Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; 4Serviço de Urologia e Transplantação Renal do Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Introduction: Diabetic nephropathy is the main global cause of end stage renal disease. According to the annual report from the Portuguese National Diabetes Observatory, in 2013, the prevalence of diabetes mellitus (DM) in new cases of chronic kidney disease was 31.2 and 11.1% in kidney transplant patients.
Aim: To characterise the population of type 2 diabetic patients admitted in diabetes and kidney transplant consult (DKTC), comparing those admitted between the decades of Jan 1992–Dec 2001 (D1) and Jan 2002–Dec 2011 (D2).
Methods: Retrospective analysis of 238 out of 332 patients admitted in DKTC (D1, n=66 and D2, n=172); the registered data included age, sex, weight, BMI, age of diagnosis, duration of DM and therapeutic, metabolic control, macro and microvascular complications at first admission. Statistical analysis was performed with SPSS.
Results: D1 patients had an average age at of 56.91±7.75 and 15.36±8.29 years of DM and a HbA1c of 7.56±1.83%. 68.2% of patients D1 had retinopathy (51.5% proliferative); 31.8% had neuropathy; 7.6% had been submitted to amputation (6.1% minor and 1.5% major); 36.4% presented macrovascular complications. 33.8% completed the selection process and were transplanted. D2 patients had an average age of 59.46±7.08 and 15.76±8.61 years of DM and a HbA1c of 7.13±1.47%. Retinopathy was present in 65.1% of D2 patients (43.1% proliferative); neuropathy in 33.1%; 8.8% had been submitted to amputation (5.9% minor and 2.9% major); 27.2% had macrovascular complications. 32.1% D2 patients were transplanted. D2 patients were older than D1 (P=0.016) but had a lower prevalence of cardiac ischemic disease (P=0.007). No other statistical significant differences were found between the two decades.
Conclusion: Diabetic patients admitted in DKTC generally have a long evolution of DM, with several co-morbidities and complications. Even though in the last decade more and older DM2 patients were referred to kidney transplantation, we did not find an increase in those patient’s complications.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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