Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2015) 37 GP22.06 | DOI: 10.1530/endoabs.37.GP.22.06

1Hospital Sant Pau, University School of Nursing, Barcelona, Spain; 2Universitat Autónoma de Barcelona (UAB) 08193 Bellaterra (Cerdanyola del Vallès), Barcelona, Spain; 3Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBER-ER), Unit 747, ISCIII, Barcelona, Spain; 4Department of Statistics and Operations Research, Universitat Politècnica de Catalunya (UPC), Barcelona, Spain; 5Intensive Care Departament, Hospital Sant Pau, Barcelona, Spain; 6Departament of Nursing. Universitat de Barcelona, Barcelona, Spain; 7Department Endocrinology, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain; 8Endocrinology/Medicine Department, Hospital Sant Pau, IIB Sant Pau, Barcelona, Spain.


Context: Cushing’s syndrome (CS) is a rare endocrine disease, due to cortisol hypersecretion. CS patients have several comorbidities, often still present after biochemical cure. There are no specific nursing healthcare programs to address this disease and achieve improved health related quality of life (HRQoL). Thus, an educational nursing intervention in these patients, through the development and promotion of specific educational tools, appears to be justified.

Objective: To assess the effectiveness of an educational nursing programme in CS patients to improve HRQoL, clinical parameters, level of pain and physical activity, patterns of rest and use of health resources.

Patient and methods: A prospective, randomized study was conducted in two reference hospitals for CS. Sixty-one patients (mean age 47±12.7 years, 83.6% females) were enrolled and divided into two groups: an ‘intervention’ group where educational sessions were performed over nine months and a ‘control’ group, without these sessions. Specific questionnaires were used at the beginning and end of the study.

Results: After the educational sessions, the intervention group had a better score in Cushing QoL (P<0.001), improved level of pain (P<0.05), physical activity (P<0.01) and healthy lifestyle (P<0.0001) compared to the control group. A correlation between the Cushing QoL questionnaire score and improvement in pain (P<0.05), physical activity (P<0.01) and sleep (P<0.01) was observed.

Conclusions: This educational nursing program improved HRQoL, physical activity, healthy lifestyle and promoted adherence to therapy and better sleep patterns in CS patients, reducing health resources consumption. The brief nature of the programme makes it a good candidate to be used in patients with CS.

Disclosure: Ma Antonia Martínez-Momblán received an unrestricted grant from Novartis as an investigator initiated study. The other authors have nothing to disclose.

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