ECE2015 Eposter Presentations Thyroid (non-cancer) (160 abstracts)
Descriptive analysis of a series of 1567 thyroidectomies in Castilla La Mancha and its association with thyroid cancer
Enrique Castro 1 , Sandra Herranz 5 , Manuel Delgado 2 , Dulce Calderón 4 , Jose Joaquin Alfaro 3 , Julia Sastre 1 & Florentino Del Val 1
1Hospital Virgen de la Salud, Toledo, Spain; 2Hospital General Ciudad Real, Ciudad Real, Spain; 3Hospital General de Albacete, Albacete, Spain; 4Hospital Virgen de la Luz, Cuenca, Spain; 5Hospital Universitario, Guadalajara, Spain.
Introduction: We wanted to analyse the descriptive variables of a series of 1567 thyroidectomy patients between 2010 and 2013 and its association with malignancy in our series.
Material and methods: Retrospective, multicentre study done by review of the medical records of 1567 patients who became thyroidectomy between 2010 and 2013 in eight sanitary areas. This is an analysis of clinical and demographic variables.
Results: The percentage of women/men was 82%/18%. The mean age was 51.8 years (S.D. 15). For the following variables, median and IC range were: time tracking: 1 year (0–3); number of visits 3 (2–6); number of scans performed 1 (1–3); and cytological studies 1 (1–2). 60.9% of patients had a family history of thyroid disease. Thyroid cancer in the family: 3.3% of cases (52 patients). Goitre/nodule was incidental in 30.8% of cases. The reasons for surgical indications were: cytological findings (33.1%); size without compressive symptoms (26%), ultrasound findings (13.5%), compressive symptoms (11.9%); hyperthyroidism 11.6% (4.3% for Graves’ disease); growth (9.9%) express wish of the patient (5.5%); lymphadenopathy (3.8%); hardness (1.1%); previous neck irradiation (0.4%); and recurrent nerve injury (0.3%).
Conclusions: In a multivariate analysis to predict malignancy were significant variables with OR: male sex 1.44 (1.023–2.05) (P=0.037); family history of thyroid cancer: 2.43 (1.23–4.8) (P=0.010); cytology as surgical indication 3.15 (2.29–4.33) (P=0.000); growth as an indication 2.1 (1.23–3.5) (P=0.006); non-existence of compressive symptoms 1.92 (1.13–3.29) (P=0.017); no size criterion as indication 1.66 (1.13–2.45) (P=0.011); no hyperthyroidism 4.06 (1.8–9) (P=0.001); and no incidental finding 1.46 (1.03–2.07) (P=0.03).
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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