ECE2015 Eposter Presentations Thyroid (non-cancer) (160 abstracts)
Hyperthyroidism in Internal Medicine Services in Spain (2005–2012)
Sandra Duran 1 , Judith Lopez 2 , Ana Ortolá 1 , Irene Crespo 1 , Teresa Ruiz Gracia 1 , Manuel Mendez 1 , Karla Nuñez 1 & Javier Marco 1
1Hospital Clinico San Carlos, Madrid, Spain; 2Hospital Universitario de Canarias, San Cristobal de la Laguna, Spain.
Introduction: The prevalence of hyperthyroidism in patients admitted in Internal Medicine at Spanish hospitals is 0.8%. Proper diagnosis and management of HTD in these patients is still a challenge and therefore, the analyses of the factors involved in the prognosis and survival is of interest.
Methods: Data from the minimum-data-set (MDS) of Spanish National health System were collected during 2005–2012 from discharged patients of Internal Medicine with HTD diagnosis. A bivariate analysis was performed in order to detect differences in the mortality rate, median age, median hospital stay, readmission rate and comorbidities among HTD and non HTD (NHTD) patients. A logistic regression analysis was performed using as dependent variable in-hospital mortality and sex, mean age, adjusted comorbidities measured by the Charlson’s index and HTD as independent variable. χ2 and Student’s t-test were performed. SPSS22.
Results: A total of 32 515 out of 3 952 018 (0.8%) cases of HTD were found with a 66% of women vs 47.1% in NHTD (P<0.001). Mean age was 77 (S.D. 12.71) years vs 72 (S.D. 17.06) in NHTD. Atrial fibrillation was more common in HTD (41% vs 22%; P<0.001), and heart failure was more frequent in HTD (33% vs 21%; P<0.0001). The mortality rate in HTD was lower than in NHTD (8% vs 10%; P<0.001). In the logistic regression analyses adjusted by age, sex, and Charlson’s cormibility index, HTD was found to be an independent factor to prevent mortality in inpatients OR 0.69 (CI: 0.66–0.74; P<0.0001).
Conclusions: HTD patients admitted to Internal Medicine wards have a lower mortality than NHTD. The frequency of women, atrial fibrillation and heart failure was higher in the HTD group. It is still unknown why HTD patients show lower mortality during admission. Perhaps other clinical and therapeutical factors, which have not been assessed through this retrospective study, have been involved with the hospital prognosis.
Volume 37
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