ECE2015 Eposter Presentations Thyroid (non-cancer) (160 abstracts)
Nondiagnostic fine-needle aspiration biopsy results: our clinic experience
Sevilay Ozmen 1 , Ilknur Calik 1 , Ebru Sener 1 , Esref Kabalar 1 , Ozge Timur 2 , Hakan Sevimli 2 , Ayse Carlioglu 3 & Senay Arikan Durmaz 3
1Department of Pathology, Training and Research Hospital, Erzurum, Turkey; 2Department of Internal Medicine, Training and Research Hospital, Erzurum, Turkey; 3Department of Endocrinology, Training and Research Hospital, Erzurum, Turkey.
Adequacy of thyroid fine-needle aspiration (FNA) is generally defined by the thyroid follicle cells, amount, and quality of colloid. Samples priorly should be evaluated for adequacy. A set of qualifying criteria are specified in Bethesda system to remove subjectivity from the adequacy assessment. Each sample prepared from a thyroid FNA should be monitored at least six follicles cell groups containing at least ten cells. In addition to these criteria of assessing the adequacy, the quality of preparation is also very important. Follicular cells should able to observe, the blood or clots should not cover the preparation and painting should be made fine. Our clinic evaluation results of FNA biopsy (FNAB) are reported as non-diagnostic for 69 patients; 54 females and 13 males. All the patients reported as non-diagnostic were operated without re-biopsy. As these patients evaluated after operation 57 of them; 44 females and 13 males diagnosed as nodular goitre (81.5%), four adenomatous hyperplasia (7%), one diffuse hyperplasia (1.8%), one papillary carcinoma (1.8%), three follicular adenoma (5.4%), and one Hürthle cell adenoma (1.8%). Patients with non-diagnostic FNAB results evaluated after operation with histopathological preparations and reported 96.4% benign and 3.6% malignant. Most of the nodules with non-diagnostic/inadequate FNAB evaluated as benign. These results bring a question to mind; should these patients operated immediately? As Bethesda’s clinical approach, patients with non-diagnostic FNAB should be re-aspirated after 3 months. To avoid false positive results depending on regeneration, there must be at least 3 months between two aspirations. We believe such an approach would protect patients from unnecessary surgery.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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