ECE2015 Eposter Presentations Thyroid cancer (90 abstracts)
Primary squamous cell carcinoma of the thyroid: a rare type of thyroid cancer
Pinar Sisman 1 , Ahmet Bilgehan Sahin 2 , Hande Peynirci 1 , Ozen Oz Gul 1 , Soner Cander 3 , Erdinc Erturk 1 & Canan Ersoy 1
1Uludag University Medical School Department of Endocrinology and Metabolism, Bursa, Turkey; 2Uludag University Medical School Department of Internal Medicine, Bursa, Turkey; 3Sevket Yilmaz Training anr Research Hospital Clinic of Endocrinology and Metabolism, Bursa, Turkey.
Introduction: Primary squamous cell carcinoma (PSCC) of thyroid is a rare type of thyroid malignancies because thyroid gland lacks squamous epithelium. It is seen in <1% of all thyroid malignancies. During last 30 years only about 90 cases were published. PSCC is an aggressive tumour as well as rare.
Case report: We present a 60-year-old female who had been followed up for multiple nodules in thyroid in our outpatient clinic for 2 years. Her serum free thyroxine (fT4), free triiodothyronine (fT3) and TSH levels were 0.9 ng/dl, 1.8 pg/ml, and 3.8 μIU/ml, respectively Her first fine needle aspiration cytology (FNAC) was benign. During follow-up because of sonographic features of nodul in left lobe, we performed the second FNAC which was suspicious for malignancy. Then total thyroidectomy was performed. In histopathological examination, well differentiated squamous cell carcinoma was revealed. Lymphovascular invasion was not seen. After surgery there was no increased glucose metabolism on F-18-fluorodeoxyglucose positron emission tomography. 21 months have passed after surgery and she had no complaint. She is going on the follow-ups.
Conclusion: PSCC of thyroid is rare but aggressive malignancy comparing with other thyroid cancers. FNAC is important for diagnosis like other types. It seems complete surgical eradication of tumour is the main treatment in PSCC of thyroid. But to achieve this, early and accurate diagnosis is important.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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