ECE2015 Eposter Presentations Thyroid cancer (90 abstracts)
Fine needle aspiration cytology, do cytology technicians make the difference?
Ricardo Capitao , Catarina Moniz , Catarina Sararaiva , Rute Ferreira , Clotilde Limbert , Marlene Carriço , Maria Carvalho , Claudia Linares , Diamantina Branco , Sancia Ramos , Isa Martins , Jose Duraes & Carlos Vasconcelos
Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Introduction: The fine needle aspiration cytology (FNAC) of thyroid nodules is the procedure of choice in the diagnostic approach of nodular thyroid disease. Despite showing a sensitivity of 83% and a specificity of 92%, many of the results are non-diagnostic. One of the factors that can contribute to this number is the proper procedure of the smear.
Objective: To compare the FNAC’s results in our team with and without the contribution of an expert Cytology Technician (CT).
Methods: All FNACs results (based on Bethesda classification) were registered in the period of 2 consecutive years in our hospital. The results were distributed between two groups: – Group A: 01/01/2013 to 31/12/2013 without CT support. Group B: 01/01/2014 to 31/12/2014 with CT support.
Results: The total of FNACs obtained was 3107 (1538 in Group A and 1569 in Group B). Benign lesions were the most frequent diagnosis in both groups. A statistical relationship between the presence of a CT and the Bethesda classification in the evaluation of FNACs was obtained (χ2 test, P<0.001). There were also a significantly more nodules with a non-diagnostic result in the Group A (χ2 test, P<0.001) than in Group B (33% vs 25% respectively). The Benign lesions and follicular Neoplasm were significantly more frequent in Group B (59.1 and 1.5%) when compared to Group A (53.0 and 0.6%), (χ2 test, P<0.001 for benign lesions; P<0.05 for follicular neoplasms). There was no significantly difference in the results of atypia of undetermined significance, suspicious for malignancy and malignant with or without CT.
Conclusions: The presence of a CT had an impact on results of FNAC, diminishing the number of non-diagnostic results and increasing the results of benign lesions and follicular neoplasms.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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