Endocrine Abstracts

Aim: To assess efficacy of training and achievement of therapy targets in children and adolescents with type 1 diabetes mellitus in ‘Diabetes Schools’.

Materials and methods: The 5-day training course was conducted in ‘Type 1 Diabetes School’ at the Center for the Scientific and Clinical Study of Endocrinology, Uzbekistan Public Health Ministry (Tashkent). The training was conducted by means of a structured program containing all appropriate sections. Before and after training course all participants were tested with a questionnaire containing 30 key questions for self-control. On the basis of the findings children and adolescents with type 1 diabetes mellitus were divided into groups. 54 of 80 children and 38 of 57 adolescents were preliminary trained, 26 children and 19 adolescents got no training. DS5 Glycomat (USA) was used to measure HbA1c by means of high pH anion-exchange liquid chromatography. Certified by the National Glycohaemoglobin Standardization Program this method became the reference one. It helps demonstrate the predicting role of HbA1c level as a criterion for assessment of chronic glycaemia and achievement of therapy targets in children and adolescents with type 1 diabetes mellitus.

Results and discussion: Frequency of target HbA1c level (≤7.5%) achievement in the trained patients was 68%. Among children who got no preliminary training target HbA1c level was found in 12%. Among trained adolescents 58% achieved compensation. The target HbA1c level was found in 11% of adolescents who got no training.

Conclusions: Frequency of target HbA1c level (≤7.5%) achievement was found in 68% of children with type 1 diabetes mellitus having received preliminary training at ‘Diabetes School’ to be significantly higher (P<0.001) than the one in the group of patients who got no preliminary training (12%). Among adolescents target HbA1c level achievement was observed in 58% of the trained patients to be significantly higher (P<0.001) as compared with those who got no preliminary training (11%). Better compensation and higher frequency of target HbA1c level achievement in children as compared with those among adolescents confirms the role of family in the type 1 diabetes mellitus control.