ECE2015 Eposter Presentations Pituitary: basic and neuroendocrinology (62 abstracts)
Hyponatremia and mortality in patients hospitalised for heart failure (2005–2011)
Javier Marco 1 , Irene Crespo 1 , Ana Ortolá 1 , Teresa Ruiz Gracia 1 , Paz De Miguel 1 , Manuel Mendez 1 , Karla Nuñez 1 , Judith Lopez 2 & Alejandra Duran 1
1Hospital Clinico San Carlos, Madrid, Spain; 2Hospital Universitario de Canarias, San Cristobal de la Laguna, Spain.
Introduction: Hyponatremia is the most frequent electrolyte disorder in hospitalised patients. Our aim was to determine the incidence, mean hospital stay, readmission rate and mortality rate among patients with acute heart failure (HF) and hyponatremia.
Methods: Retrospective analysis of data collected from the minimum data set (MDS) of Spanish National health System during 2005–2012 from discharged patients of Internal Medicine with HF and hyponatremia. A bivariate analysis was conducted in order to detect differences in the mortality rate, mean hospital stay and readmission. A logistic regression analysis was performed using as dependent variable in hospital mortality, adjusted for age and Charlson’s index. χ2 and Student’s t-tests were performed.
Results: A total of 11 095 (2.2%) out of 504.860 cases with HF presented hyponatremia and 64.6% were women. Mean age was 81.9 (S.D.: 9.27) years in hyponatremia groups vs 79.7 (S.D.: 9.76) in normonatremic patients. In our study we found an increased prevalence of encoded hyponatremia as the mean diagnosis, from 7.7% in 2005 to 24.4% in 2011. The overall mortality in hyponatremic patients was 17.5% vs 10.9% (P<0.001) in non hyponatremic. Readmission rate was 22.2% vs 16.8% (P<0.001). Hyponatremia was associated with an increased risk of mortality, with an OR 1.58 (95% CI 1.50–1.66); P<0.05. The same results were found in the logistc regression analyses adjusted for age (OR 1.061 (95% CI 1.060–1.062); P<0.05) and for Charlson’s index (OR 1.388 (95% CI 1.361–1.461); P<0.05).
Conclusions: Hyponatremia was associated with an increased mortality risk in hospitalised patients with HF, as described in previous studies. Thus, its accurate diagnosis and treatment is crucial. Nowadays, hyponatremia is considered to be a mayor diagnosis as reflected in the increased prevalence of its coding in discharged sheets. Nonetheless, further prospective studies regarding hyponatremia and mortality are needed.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more