Endocrine Abstracts

Introduction: Micropenis is defined as a stretched penile length of <2.5 S.D., which can be diagnosed from birth to adolescence. It is idiopathic or associated with a chromosomal abnormality, hypogonadism, pituitary abnormality or a complex malformation syndrome. The therapeutic management of this disease should be early to get a favorable response and absence of impact objective. Clarify the clinical and etiological aspects of micropenis of patients followed.

Population, methodology: We made a retrospective study of the cases of patients with micropenis collected in 26 years. A clinical examination and oriented paraclinical exploration has been made.

Results: 30 patients were identified (18 children and adolescents between 2–18ans and 12 adultes between 21–44 years). The average age at the consultation is 15 years in children, 30 adults. It is isolated in 50% diagnose at an average age of 13, 5 years in children. In half of the cases, it is associated with other genital abnormalities who did reveal: it in children: cryptorchidism 12 (40%) diagnosed at 5 years (only on at birth) lifts testicles: 2 (6%), hypospadias 1 (3%). The reason for consultation was the signs of hypogonadism in adults in all cases. Aetiological, it is due to a central hypogonadism (40%), GH deficiency (7%) and gonadal dysgenesis (3%). 50% of cases are idiopathic. In half of cases micropenis children (mainly idiopathic and pituitary) responded favourably to androtardyl and GHR in the case of GH deficiency. The younger children (<6 years) responded best.

Discussion and conclusion: The absence of systematic examination of the external genitalia at birth and ignorance of these abnormalities explain the delay in diagnosis and ineffectiveness of treatment. Progress height-weight and hairiness induced by the treatment did not reconsider the treatment against the benefit obtained.