ECE2015 Eposter Presentations Diabetes (pathiophysiology & epitemiology) (80 abstracts)
Unawareness hypoglycaemia in patients with type 1 diabetes mellitus: prevalence and predictive clinical characteristics
Mariola Méndez Muros , Eyveé Arturo Cuéllar Lloclla , Fernando García Pérez , Guillermo Martínez de Pinillos Gordillo , Mariana Tomé Fernández-Ladreda , Juan Manuel Garcíade Quirós Muñoz , José Ignacio Fernández Peña , José Ignacio Fernández López , Margarita Rivas Fernández , Juana Magdalena Hidalgo Amat , Santiago Durán García & María Victoria Cózar León
Valme University Hospital, Seville, Spain.
Background: The prevalence of unawareness hypoglycaemia in patients with type 1 diabetes mellitus (T1DM) is uncertain. This study aims to determine its prevalence and predictive clinical characteristics with greater precision.
Methods: Prospective study. 128 patients were recruited between September 2013 and January 2014. Awareness of hypoglycaemia was assessed using the ‘Clarke’ questionnaire and was classified into two groups, depending on the presence (group 1) or absence (group 2) of symptoms perception.
Results: The ‘Clarke’ questionnaire was completed by 128 patients with T1DM: 53.8% females; mean age 36.2±12.8 years; duration of diabetes 15.65±9.18 years; HbA1c 7.45±1.35%; 87.5% used intensive insulin therapy with multiple insulin doses. 80 patients (62.5%) were included in group 1 and 48 (37.5%) in group 2. The frequency of at least one episode of severe hypoglycaemia during the previous year was 20.3% in group 1 and 37.5% in group 2. 43% of patients in group 1 and 56.3% in group 2 needed a blood glucose value <50 mg/ml to notice symptoms. 43% of patients in group 1 and 66.7% in group 2 considered their symptoms hardly ever or never warned them about the presence of hypoglycaemia. There have not been any significant differences between both groups in diabetic microangiopathy, duration of disease, eating disturbances and insulin regimens (basal-bolus vs biphasic).
Conclusions: We have observed a high prevalence of unawareness hypoglycemia in patients with T1DM. Educational strategies are needed to improve their perception of hypoglycaemia symptoms.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more