ECE2015 Eposter Presentations Diabetes (pathiophysiology & epitemiology) (80 abstracts)
Maintenance of risk reduction during 3-year follow up in prevention of type 2 diabetes by lifestyle intervention in primary health care setting: Diabetes in Europe Prevention using Lifestyle, physical Activity and Nutritional intervention (DE-PLAN) project
Aleksandra Gilis-Januszewska 1 , Beata Piwonska-Solska 1 , Zbigniew Szybinski 1 , Katarzyna Kissimova-Skarbek 2 , Roman Topor-Madry 2 , Grzegorz Glab 5 , Jaana Lindstrom 3 , Marku Peltonen 3 , Peter Schwarz 4 , Dorota Pach 1 , Jaakko Tuomilehto 3 & Alicja Hubalewska-Dydejczyk 1
1Chair and Department of Endocrinology, Jagiellonian University, Krakow, Poland; 2Institute of Public Health, Jagiellonian University, Krakow, Poland; 3Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; 4Department of Medicine III, Carl Gustav Carus of the Technical University Dresden, Dresden, Germany; 5Department of Rehabilitation, Faculty of Physiotherapy, University School of Physical Education, Krakow, Poland.
Introduction: Extended up to 20 years follow-up of several randomised control trials showed 34–43% diabetes risk reduction. Real life implementation studies performed worldwide in different settings and populations proved that also non-intensive, low budget lifestyle interventions can be effective. However little is known about long-term results of the translational studies.
Objective: To study the risk factors changes of the DEPLAN non-intensive lifestyle intervention in primary health care setting during 3-year follow up.
Research design and methods: Study participants (n=114) with baseline diabetes type 2 risk FINDRISC >14, no diabetes, received ten group lifestyle counselling sessions, six motivation phones, and two letters and physical activity. Measurements performed at 12 months after the initiation of the intervention were repeated after 36 months.
Results: Statistical significant risk reduction at 1 year was maintained at 3 years in weight (82.9 vs 81.6 kg), BMI (31.2 vs 30.1 kg/m2), serum total cholesterol (5.5 vs 5.4 mmol/l), TG (1.85 vs 1.6 mmol/l (P<0.09)), and FINDRISC (18.4 vs 16.2 (P<0.05)). After 3 years 6% of participants converted to diabetes, while 56% of baseline IFG and IGT reversed to NGT. Physical activity increase, increased consumption of vegetable and fruit and decreased of saturated fat and change of saturated fat to unsaturated observed at one year were also maintained during follow up (P<0.05).
Conclusions: Diabetes type 2 prevention through non intensive, real life lifestyle intervention with modest weight reduction is feasible in a primary health care setting and can be maintained during long time observation.
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Endocrine Abstracts
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