Endocrine Abstracts

Introduction: Hyperprolactinemia is a common endocrine condition causing galactorrhoea. Breast abscess is a frequent complication of the post partum period and breast feeding but it rarely occurs out of these two situations. We report the case of a patient presenting with tumoural hyperprolactinaemia associated with a breast abscess.

Case report: A 34 years-old patient presented with galactorrhoea, spaniomenorrhoea and headache for six months. She had nothing special in her medical history and was not on drugs. She was the mother of two children aged eight and four. Prolactine assessment was made twice and confirmed the hyperprolactinaemia (Prolactine: 94 and 110 ng/ml). Pituitary MRI concluded to a pituitary microadenoma so that microprolactinoma was diagnosed and the patient put on dopaminergic agonists. 15 days later, the patient suddenly developed a painful mass of the left breast. Biologic assessment showed an inflammatory syndrome with hyperleucocytosis. The breast ultrasound examination revealed an abscess of 4 cm in the superior external quadrant, with no other abnormalities of the breast. The course of the abscess was good on antibiotics (Amoxicillin+clavulanic acid) and surgery was not indicated.

Conclusion: This case report highlights the fact that during pathological hyperprolactinaemia, the histology of the breast glands may be modified leading to a risk of developing breast abscess. This phenomenon is may be exactly the same than during breastfeeding. No other similar cases have been reported in the literature.