Endocrine Abstracts

Contents

• Speaker Abstracts
• • CME Session
  • • Endocrine tumours

      ea0036cme1
    • Surgery of endocrine tumour

      ea0036cme2
    • The late effects of treatment for childhood cancer

      ea0036cme3
    • Female contraception and reproductive endocrinology

      ea0036cme4
    • Infertility and infertility management

      ea0036cme5
    • Trainees update

      ea0036cme6
• Main Symposia
• • Plenary Guest Lecture
  • • The future of the child with T1DM

      ea0036pl1
  • Symposia 1 Controversies in Vitamin D deficiency
  • • Consequences of maternal vitamin D deficiency

      ea0036s1.1
    • The role of vitamin D deficiency in unexplained fractures of infancy

      ea0036s1.2
    • Strategies for prophylaxis and treatment of vitamin D deficiency

      ea0036s1.3
  • Symposia 2 Recent advances in adrenal disease
  • • Adrenal development and adrenal insufficiency

      ea0036s2.1
    • Curing Addison's disease

      ea0036s2.2
  • Symposia 3 New developments from trials in TIDM
  • • New developments from trials in TIDM: findings from the DECIDE trial

      ea0036s3.1
    • How do the findings from the Hvidore study change practice?

      ea0036s3.2
    • Prevention trials in type 1 diabetes', including an update on the ongoing TRIGR trial

      ea0036s3.3
  • Debate: Children with diabetes should be managed centrally
  • • Children with diabetes should be managed centrally

      ea0036d1.1
    • Children with diabetes should be managed locally

      ea0036d1.2
  • Diabetes Professionals Session
  • • Paediatric obesity and type 2 diabetes

      ea0036dp1
    • Type 2 diabetes

      ea0036dp2
    • Hypoglycaemia in type 1 diabetes mellitus

      ea0036dp3
    • National Audit Data highlight persistent sub-optimal control among increasing numbers of people living with diabetes with severe consequences for the individual and the NHS

      ea0036dp4
    • School care plans

      ea0036dp5
    • Fat and Protein counting: what's the evidence?

      ea0036dp6
    • BPT

      ea0036dp7
  • Endocrine Nurse Session
  • • Genetics: back to basics

      ea0036en1
    • Breathe-easy - the significance of respiratory assessment in Prader-Willi syndrome

      ea0036en2
    • Sleep easy: the practicalities of sleep study

      ea0036en3
    • Patient experience

      ea0036en4
    • Home grown: PENS vs homecare GH start

      ea0036en5
• Oral Communications
• • Oral Communications 1
  • • Paediatric pituitary adenomas: rare, complex, and by no means benign

      ea0036oc1.1
    • Functional adrenal tumour as a cause of virilised infant

      ea0036oc1.2
  • Oral Communications 2
  • • Unilateral gynecomastia: an unusual presentation of Peutz Jegher's syndrome

      ea0036oc2.1
    • Isodicentric chromosome Y mosaicism in a female patient: an indication for gonadectomy

      ea0036oc2.2
  • Oral Communications 3
  • • The Scottish audit of atypical genitalia: first year results

      ea0036oc3.1
    • Vertebral fracture assessment in a paediatric population using dual-energy X-ray absorptiometry

      ea0036oc3.2
    • An analysis of meta-data from three UK centres on the sequelae of paediatric craniopharyngiomas over four decades

      ea0036oc3.3
    • Standard population screening for diabetes mellitus has low sensitivity in identifying diabetes in adult survivors of childhood bone marrow transplantation with total body irradiation

      ea0036oc3.4
    • Statistical prediction of HRpQCT microstructural trabecular parameters using 1.5T skeletal MRI

      ea0036oc3.5
    • A novel non-invasive short Synacthen test

      ea0036oc3.6
    • Patterns of gene expression in pre-pubertal children are associated with the severity of their GH deficiency

      ea0036oc3.7
    • Trends in off-label prescription of GH: results from the National GH Audit

      ea0036oc3.8
    • Physiological dose reverse rhythm testosterone treatment abolishes the development of permanent gynaecomastia in adolescents with 47,XXY Klinefelter syndrome

      ea0036oc3.9
  • Oral Communications 4
  • • Utility of basal LH in comparison to the GnRH test for identifying central precocious puberty in girls

      ea0036oc4.1
    • Validation of a Food Frequency Questionnaire for rapid assessment of daily dietary calcium intake in children

      ea0036oc4.2
    • A role for delta-like homologue 1 in a secretory placental population and implications for fetal growth

      ea0036oc4.3
    • Expression of Sonic hedgehog signalling components in the developing human adrenal cortex

      ea0036oc4.4
    • Adiposity differs by fracture site in children with upper limb fractures

      ea0036oc4.5
    • Evaluating dipeptidyl peptidase-4 expression in patients with diffuse and focal congenital hyperinsulinism.

      ea0036oc4.6
    • Pitfalls in the diagnosis of neonatal adrenal insufficiency

      ea0036oc4.7
    • Recombinant human GH in paediatric inflammatory bowel disease: short term effects on bone biomarkers and long term effects on bone and lean mass

      ea0036oc4.8
    • Neurodevelopmental phenotypes in children with early and late presenting congenital hyperinsulinism

      ea0036oc4.9
  • Oral Communications 5
  • • Congenital adrenal hyperplasia: a survey on the current practice in UK

      ea0036oc5.1
    • The impact of receiving a diagnosis of congenital hypothyroidism on families

      ea0036oc5.2
    • Does treatment with GnRH analogues affect BMI in children with precocious or early puberty?

      ea0036oc5.3
  • Oral Communications 6
  • • Exploring variation in treatment targets across paediatric diabetes units in England and Wales

      ea0036oc6.1
    • The diabetic pregnancy and offspring adiposity in infancy and childhood: a meta-analysis

      ea0036oc6.2
    • Comparison of breath acetone, with blood glucose and blood ketones in children and adolescents with type 1 diabetes

      ea0036oc6.3
    • The role of the AMPK pathway in mediating the effects of metformin on mesenchymal stem cell differentiation

      ea0036oc6.4
    • Capillary beta-hydroxybutyrate levels reliably predicts clinical severity in established diabetes but not in first presentations of type 1 diabetes in children

      ea0036oc6.5
    • Comparison of type 1 diabetic control before and 5 years after transfer to adult services: audit of the 2008 cohort from the Royal Hospital of Sick Children (RHSC), Glasgow

      ea0036oc6.6
  • Oral Communications 7
  • • Additional professional support for paediatric patients with diabetes mellitus: are we targeting the right patients?

      ea0036oc7.1
    • Urinary vitamin E metabolites as a biomarker of oxidative stress in type 1 diabetes

      ea0036oc7.2
    • Do diabetes teams give consistent advice on self-management and does it relate to glycaemic control? Yorkshire and Humber Paediatric Diabetes network survey

      ea0036oc7.3
    • Hyperosmolar hyperglycaemic state: an unusual presentation of type 2 diabetes mellitus in children

      ea0036oc7.4
    • The relationship of vibration perception threshold with metabolic control and duration of disease in British children with type 1 diabetes

      ea0036oc7.5
• Poster Presentations
• • (1)
  • • A rare cause of iatrogenic Cushing's syndrome

      ea0036P1
    • A unique case of a child with two inherited salt-losing conditions

      ea0036P2
    • Aldosterone synthase deficiency due to a novel mutation in CYP11B2

      ea0036P3
    • cDNA analysis reveals NNT pseudoexon activation in two siblings with familial glucocorticoid deficiency

      ea0036P4
    • Cerebral oedema: a rare presentation of Addison's disease

      ea0036P5
    • Comparing clinical practice with consensus guidelines for the investigation and management of British children with congenital adrenal hyperplasia

      ea0036P6
    • Congenital adrenal hyperplasia due to 21-hydroxylase deficiency in a regional cohort 1994-2004: characterisation and genotype-phenotype analysis

      ea0036P7
    • Do babies born to mothers taking antenatal prednisolone require screening for adrenal suppression?

      ea0036P8
    • Functional adrenal tumour as a cause of virilised infant

      ea0036P9
    • Severe hyponatraemia and pseudohypoaldosteronism secondary to infantile atopic dermatitis

      ea0036P10
    • The accuracy of 24-h urinary free cortisol as a screening test in the diagnosis of Cushing's syndrome in children

      ea0036P11
    • Varied clinical presentations of six patients with mutations in CYP11A1 encoding the cholesterol side-chain cleavage enzyme, P450scc

      ea0036P12
    • Development of a premature adrenarche management guideline

      ea0036P13
    • Bone mineral density and vertebral compression fractures in patients with recessive dystrophic epidermolysis bullosa

      ea0036P14
    • Hyperostosis-hyperphosphataemia syndrome: shortening a diagnostic odyssey

      ea0036P15
    • Leptin is associated with bone microstructural changes in obese children

      ea0036P16
    • Neonatal seizure: a rare presentation of maternal hyperparathyroidism

      ea0036P17
    • Suppression of bone turnover and its determinants in children receiving bisphosphonate therapy

      ea0036P18
    • Young adults with Klinefelter syndrome and congenital anorchia treated with testosterone from adolescence have normal bone and muscle mass but increased central adiposity

      ea0036P19
    • Denosumab therapy for refractory hypercalcaemia secondary to squamous cell carcinoma of skin

      ea0036P20
    • Hypercalcaemia, hypercalciuria and nephrocalcinosis secondary to a CYP24A1 mutation

      ea0036P21
    • An unusual presentation of eating disorder in type 1 diabetes

      ea0036P22
    • Audit of insulin doses in children with newly diagnosed type 1 diabetes

      ea0036P23
    • Be wary of hyperglycaemia in newborn: a case of monogenic permanent neonatal diabetes

      ea0036P24
    • Bone markers in children with type 1 DM

      ea0036P25
    • Can proportion of children achieving HbA1c below 58 mmol/mol within the first year of diagnosis be used as a standard of quality of care provided for children with type 1 diabetes?

      ea0036P26
    • Children with type 1 diabetes and coeliac disease at Nottingham Children's Hospital: a service review and evaluation

      ea0036P27
    • Diabetes A[amp]E attendances and ward admissions pre and post implementation of an out of hours telephone service

      ea0036P28
    • Does continuous subcutaneous insulin infusion therapy improve diabetic control in a district general hospital population?

      ea0036P29
    • Epidemiology and risk factors for diabetic retinopathy in CYP with type 1 diabetes mellitus in a DGH

      ea0036P30
    • Eruptive xanthomas as a presenting feature of diabetes mellitus

      ea0036P31
    • How effective was the national '4T's' diabetes awareness campaign for a local paediatric population and did specific interventions reduce admissions for DKA?

      ea0036P32
    • Improving the clinical pathway for diabetic retinal screening in paediatric diabetes

      ea0036P33
    • In-patient care for children with type 1 diabetes across hospitals in the Yorkshire and Humber region in the north of England

      ea0036P34
    • Kaempferol, a dietary flavonoid improves glucose homeostasis in streptozotocin diabetic tissues by altering glycolytic and gluconeogenic enzymes

      ea0036P35
    • Lessons learnt from starting an insulin pump service in Forth Valley, Scotland: challenges, solutions, and outcomes

      ea0036P36
    • Management of paediatric diabetic ketoacidosis: are we doing it right?

      ea0036P37
    • An evaluation of a hospital-based diabetes education program provided for schools and nurseries

      ea0036P38
    • Meeting the training needs of paediatric trainees in managing children with diabetes

      ea0036P39
    • Neonatal diabetes: the great masquerader experiences from one hospital

      ea0036P40
    • Prevalence, clinical profile, and glycemic variability of celiac disease in patients with type 1 diabetes mellitus in western, Uttar Pradesh, India

      ea0036P41
    • Prognostic factors in patients hospitalised with diabetic ketoacidosis

      ea0036P42
    • The effect of the introduction of best practice tariff for paediatric diabetes care on service provision and staffing in the West Midlands

      ea0036P43
    • Transition and beyond in childhood onset type 1 diabetes

      ea0036P44
    • Using an electronic tablet to survey patient satisfaction in an adolescent transitional diabetes clinic at York, United Kingdom

      ea0036P45
    • Visual disturbance in diabetes mellitus: don't be blind to alternatives to retinopathy

      ea0036P46
    • An ovulating testis

      ea0036P47
    • Initial care of babies born with ambiguous genitalia: a service evaluation

      ea0036P48
    • Pubertal gynaecomastia: when is reverse rhythm testosterone treatment in adolescent boys with delayed puberty effective?

      ea0036P49
    • Sex chromosome mosaicism in males: our experience

      ea0036P50
    • What is the optimum cardiovascular screening in Turner syndrome during childhood and adolescence? Is it achievable?

      ea0036P51
    • Improving health-related outcomes for childhood craniopharyngiomas with a modern individualised conservative surgical strategy and adjuvant focussed radiation; experience at a single centre (great ormond street hospital [ndash] GOSH) 2009[ndash]2013

      ea0036P52
    • Bone age study in children (BASIC): a study of the quality of bone age X-rays and an intervention to improve quality and reduce re-X-ray rates

      ea0036P53
    • Transient hyperphosphatemia and hyperparathyroidism in a preterm neonate

      ea0036P54
    • Journey through setup of adolescent gender identity dysphoria service for Notheren Ireland

      ea0036P55
    • Low birth weight is not a feature of polycystic ovarian syndrome in a British cohort of adolescents, but obesity and metabolic syndrome are common associations

      ea0036P56
    • Effect of vitamin D treatment on glucose and insulin metabolism, and bone turnover in children with symptomatic vitamin D deficiency

      ea0036P57
    • An audit of paediatric obesity in secondary care

      ea0036P58
    • Is there a role for medical management in childhood obesity? A review of the Manchester Metabolic Obesity Service

      ea0036P59
    • Melanocortin 2 receptor accessory protein 2 (Mrap2) regulates hypothalamic melanocortin-4-receptor trafficking in vivo

      ea0036P60
    • Challenges of managing a 9-month old child with congenital hyperinsulinism within a secondary care setting

      ea0036P61
    • Lanreotide therapy for congenital hyperinsulinism

      ea0036P62
    • Hyperinsulinaemic hypoglycaemia and cochlear hypoplasia in a rare case of Pallister-Hall syndrome

      ea0036P63
    • Cellular proliferation is increased in both the lesion and non-lesion pancreas in focal congenital hyperinsulinism

      ea0036P64
    • A heterozygous STAT5B variant in a family with short stature and transient hyperprolactinaemia: a possible dominant negative effect

      ea0036P65
    • Growth characteristics in children with Temple syndrome: an under-diagnosed imprinting disorder

      ea0036P66
    • A rare thyrotropinoma complicated by cerebral salt wasting: a case report

      ea0036P67
    • Assessing the diagnostic value of testosterone, basal LH and LHRH test in predicting pubertal progression in boys

      ea0036P68
    • Bone mass and body composition in adolescents with childhood onset GH deficiency

      ea0036P69
    • Evaluating the diagnostic value of basal LH and LHRH test in predicting progression into precocious puberty in girls

      ea0036P70
    • A novel de novo heterozygous mutation in FGFR1 is associated with Hartsfield syndrome

      ea0036P71
    • 'Can I gain a greater height?': a case of metaphyseal chondrodysplasia, Schmid-type

      ea0036P72
    • GH deficiency contributes to short stature in children with chromosome 18 rearrangements

      ea0036P73
    • Impaired insulin and IGF2 signalling in the primordial growth disorder 3-M syndrome

      ea0036P74
    • Relationship between IGF1 concentration and growth velocity in infants and toddlers

      ea0036P75
    • Septo-optic dysplasia, multiple pituitary hormone deficiency and optic nerve hypoplasia: clinical and neuroradiological characteristics

      ea0036P76
    • Thickened pituitary stalk (TPS) and/or idiopathic central diabetes insipidus (ICDI): a single centre experience of occult causative pathology evolving in 54 children over 30 years

      ea0036P77
    • Three year experience of a national interdisciplinary initiative to improve outcomes for children with hypothalamic pituitary axis tumours (HPATs) using multi-site videoconferencing for decision making on Behalf of the UK HPAT Interest Group

      ea0036P78
    • UK GH stimulation test survey

      ea0036P79
    • Variable presentation of xanthogranulomatous hypophysitis: a case series

      ea0036P80
    • A case report of TR[beta] mutation leading to raised T4 levels presenting with abnormal body habitus

      ea0036P81
    • An audit to assess the impact of increasing the borderline blood spot TSH cut-off on the detection of cases of congenital hypothyroidism (CHT) identified via newborn screening

      ea0036P82
    • Congenital central hypothyroidism due to a TSHB mutation with uniparental inheritance

      ea0036P83
    • Delayed recognition of neonatal thyrotoxicosis in a baby born to a mother previously treated for Grave's disease

      ea0036P84
    • Goitre: a presenting feature of acute myeloid leukaemia

      ea0036P85
    • Management of congenital hypothyroidism: audit of our experience over a decade vs the new national standards

      ea0036P86
    • Prevalence of short stature in juvenile hypothyroidism and the impact of treatment in a tertiary care center

      ea0036P87
    • Severe hypothyroidism developing in an infant with hepatoblastoma and Beckwith-Wiedemann syndrome: could there be a link?

      ea0036P88