ECE2014 Poster Presentations Bone and Osteoporosis (36 abstracts)
The total fat mass and the fracture risk assessment: a study in 146 Romanian menopausal women
Mara Carsote 1, , Valentin Radoi 2 , Alexandra Mihai 1 , Andreea Geleriu 1 , Rucsandra Danciulescu Miulescu 2 , Cristina Capatana 1, , Raluca Trifanescu 1, & Catalina Poiana 1,
1Parhon Institute, Bucharest, Romania; 2Davila UMPh, Bucharest, Romania.
Introduction: The fat mass (FM) is assessed by DXA, magnetic resonance, etc. One of the most accessible methods for current practice is bioimpedance.
Aim: We analyzed FM based on bioimpedance and fragility fracture risk.
Material and method: This is a transversal study in women, admitted at C.I.Parhon National Institute of Endocrinology, Bucharest, Romania. The inclusion criteria were women in menopause. The exclusion criteria were previous diagnosis of osteoporosis at DXA; previous specific therapy for osteoporosis. The fracture risk was based on left hell quantitative ultrasound (QUS: Achilles); central DXA (Lunar) providing bone mineral density (BMD); 10-year absolute fracture risk based on FRAX (risk for major osteoporotic fracture: MF, and hip fracture: HF, noted with I in case of FRAX without BMD, and II in case of FRAX with BMD). FM was expressed in percents (Tanita device). The statistical analyze used SPSS 21; statistical significance (SS) was considered at P<0.05.
Results: 146 women were enrolled (median age 57 years, mean FM: 37%). The linear regression coefficient between FM and stiffness index (QUS) was r=0.14 (SS); between FM and lumbar BMD was r=0.15 (SS); between FM and hip BMD was r=0.27 (SS); between FM and femoral neck BMD was r=0.24 (SS); between FM and MF I, respective II was r=−0.22 (SS), respective r=−0.22 (SS); between FM and HF I, respective II was r=−0.25 (SS), respective r=−0.22 (SS).
Discussion: Despite the fact that FRAX includes BMI, this is not completely overlapped with FM. The use of neck BMD in FRAX did not influence the correlation with FM. More precise methods of FM assessment will provide more data in skeleton health.
Conclusion: Positive week but statistically significant correlations were found between FM and QUS or DXA, and negative, modest but also statistically significant between FM and FRAX risk.
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Endocrine Abstracts
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