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Endocrine Abstracts (2014) 35 P266 | DOI: 10.1530/endoabs.35.P266

Pirogov Medical Center, Saint-Petersburg, Russia.


Background: It is disputable whether to repeat FNAB after the first one was nondiagnostic, or to submit the patient to operation.

Methods: Indication for FNAB was a thyroid nodule of ≥1 cm or of a less size with clinical or ultrasound features of malignancy. In case of multinodular goiter each nodule was punctured and examined separately.

3929 cases (8%) were noninformative out of 49 419 FNAB of thyroid nodules performed in North-West Regional Endocrine Center during 2010–2012 years. Among these technical mistakes occurred in 69 cases (1.7%), and insufficient amount of follicular epithelial cells was in 3861 (98.3%) of cases. Repeated FNABs were performed to all patients with nondiagnostic primary results of FNAB in 1 month after the first one. During the second FNAB, we took cell material into four glasses instead of two glasses like for the first time.

Results: 3760 (96%) of cases became informative after repeated FNAB. 168 cases remained nondiagnostic. Malignant tumours were revealed in 1.8% of cases of repeated FNAB, that is significantly lower than among primary FNAB (3%).

Conclusion: The results of the study show that repeated FNAB is very valuable diagnostic procedure, that allows to transfer the majority of nondiagnostic FNAB into group suitable for diagnostics.

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