ECE2014 Poster Presentations Cardiovascular Endocrinology & Lipid Metabolism (41 abstracts)
1Van Grieken University Hospital, Coro, Falcón, Venezuela; 2Dr. Domingo Luciani Hospital, Caracas, D.C., Venezuela; 3Clinic Universitary Hospital, Caracas, D.C., Venezuela; 4Paraguaná Polyclinic, Punto Fijo, Falcón, Venezuela; 5CESCARDIM, Maracaibo, Zulia, Venezuela; 6La Viña Polyclinic Center, Valencia, Carabobo, Venezuela; 7Santa Rosa Clinic Center, Cumaná, Sucre, Venezuela; 8ASCARDIO, Barquisimeto, Lara, Venezuela.
The 2013 guideline (NHLBI ATP IV) on the treatment of blood cholesterol in adults was recently published. It focuses on identification of 4 Statin Benefit Groups (4SBG), in which the potential for Atherosclerotic Cardiovascular Disease (ASCVD) risk reduction benefit clearly exceeds the potential for adverse effects.
Objective: To estimate the prevalence of 4SBG among Venezuelan women and to determine its association with hypertension, BMI, waist circumference (WC), fasting blood glucose, age, obesity, reproductive history, socioeconomic status, and lifestyle.
Methods: In this cross-sectional study, a sample of 527 women (4075 years old) was selected in gynecology clinics from 24 provinces of Venezuela. The levels of blood pressure, serum glucose, Col-T, HDLc, LDLc, and TG were measured for all them. 4SBG was defined according to ATP IV: i) clinical ASCVD; ii) LDLc ≥190 mg/dl; iii) diabetes and LDLc 70189 mg/dl; iv) neither ASCVD nor diabetes, LDLc 70189 mg/dl, estimated 10-year ASCVD risk ≥7.5% (by Pooled Cohort Equations).
Results: The prevalence (95% CI) of 4SBG, namely A, B, C, and D were 2.7 (1.24.0), 8.3 (6.010.7), 19.3 (16.522.6), and 8.0% (5.710.2) respectively. Overall, 61.5% (58.964.1) of women did not belong to 4SBG. WC was higher in A and C groups. Prevalences of HTA and obesity were higher in 4SBG than in non 4SBG women (P<0.001). The prevalence of 4SBG women increased steadily in line with age (P<0.001). Interestingly, the prevalence was 100% in the 70-year-old age or older Group.
Conclusions: EEM-Lipid Study data indicate that nearly 40% of the Venezuelan women (4075 years old) would require the use of statins as recommended by NHLBI ATP IV. Furthermore, for all women over age 70 would be indicated using it. Therefore, effective public health education and urgent precautions are needed.