ECE2014 Poster Presentations Calcium and Vitamin D metabolism (68 abstracts)
The relationship between microvascular complications and vitamin D deficiency in type 2 diabetes mellitus microvascular complications and vitamin D deficiency
Celil Usluogullari , Fevzi Balkan , Sedat Caner , Rifki Ucler , Cafer Kaya , Reyhan Ersoy & Bekir Cakir
Clinic of Endocrinology and Metabolism, Atatürk Training and Research Hospital, Ankara, Turkey.
Aim: Vitamin D deficiency is reported as a risk factor for the development of diabetes in several epidemiologic studies. In this study, we investigated the frequency of 25-OH vitamin D deficiency in type 2 diabetes and the relationship between 25-OH vitamin D deficiency and microvascular complications.
Materials and methods: Retrospectively, medical records of 557 type 2 diabetic patients admitted to the Endocrinology Outpatient Clinic in January–March period and 112 healthy controls who were randomly selected among individuals admitted to the hospital for a check-up and had a laboratory result of 25-OH vitamin D level were screened. The level of 25-OH vitamin D in type 2 diabetes and the relationship between 25-OH vitamin D deficiency and microvascular complications are investigated.
Results: There was not statistically significant difference in terms of 25-OH vitamin D levels between diabetic and control group. No correlation between HbA1c and vitamin D levels was found. 25-OH vitamin D level was lower in diabetic patients with nephropathy. Also patients not using any medication and followed by only dietary suggestion, had nephropathy in higher frequency.
Conclusion: Vitamin D deficiency is more common in diabetic patients with nephropathy. Upon evaluation of the total microvascular complications, vitamin D level was also lower. Vitamin D deficiency is associated with microvascular complications of diabetic patients.
Key Words: Type 2 DM, 25-OH vitamin D, microvascular complications.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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