Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2014) 35 P1078 | DOI: 10.1530/endoabs.35.P1078

ECE2014 Poster Presentations Thyroid (non-cancer) (125 abstracts)

Evaluation of cardiovascular risk factors in adults with primary hypothyroidism

Hafsa Si Joucef 1 , Ali El Mahdi Haddam 1 , Soumeya Fedala 2 , Wassila Mansouri 1 , Djamila Meskine 1 & Farida Chentli 2


1Bologhine Hospital, Algiers, Algeria; 2Bab El Oued Hospital, Algiers, Algeria.


Introduction: Hypothyroidism is a frequent pathology responsible for a significant increase in cholesterol. It is caracterized by myocardial changes, increased risk of cardiovascular disease and more particularly coronary event performance.

Aim: Assess cardiovascular risk factors in adults suffering from primary hypothyroidism.

Materials and methods: This retrospective study included data from 50 patients (44 women and 6 men) adults (age >18 years) with primary hypothyroidism acquired(non iatrogenic) whose average age at diagnosis was 47.6 years (aged 19–75) initially before prescription replacement therapy.

Results: The BMI was 27.84 kg/m2 with obesity in 43.3% of cases and 13% overweight.

The mean cholesterol is 2.01 g/l and 23.3% of patients have high cholesterol, triglycerides means of 1.37 g/l and 20% of patients have a hypertriglyceridemie. 26.6% of patients have hyper blood pressure (hypertension) and 10% had diabetes mellitus type 2. coronary artery disease is diagnosed in 13% of cases and was significantly associated with age and hypertension.

Conclusion: The thyroid hypofunction is the cause of lipid disorders that enhances cardiovascular risk and increases morbidity and mortality. Atherosclerosis is more severe because it associates with several cardiovascular factors.

Our highlight of results frequency of overweight, dyslipidemia, hypertension and diabetes mellitus. They must be systematically sought and reassessed in euthyroidism.

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