ECE2014 Symposia Long term outcome of cured pituitary patients (3 abstracts)
Quality of life in patients with non-functioning pituitary adenomas
Cristina Capatina 1 , Constantinos Christodoulides 2 , Alberto Fernandez 2 , Simon Cudlip 3 , Ashley Grossman 2 , John Wass 2 & Niki Karavitaki 2
1C.I.Parhon National Institute of Endocrinology, Bucharest, Romania; 2Department of Endocrinology, Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK; 3Department of Neurosurgery, John Radcliffe Hospital, Oxford, UK.
Non-functioning pituitary adenomas (NFA) are associated with significant morbidity. Published data on the quality of life (QoL) of NFA patients are scarce and conflicting: some studies indicate a reduced QoL in patients with adequately treated NFAs while others demonstrate that subjective health-related QoL is not compromised to any major extent compared to the general population. Most published studies indicate specific subgroups of patients which are particularly affected, with various types of pituitary insufficiency, radiotherapy, age and gender being the factors most commonly found to have a significant measurable impact upon the QoL of treated NFA patients.
The objective of this talk is to review some of the discordant findings in the literature and to briefly present our own recent work aimed to evaluate the QoL in NFA patients followed-up in a tertiary endocrine UK referral centre.
This will hopefully help to highlight some practical measures to prevent relevant factors with a negative impact on QoL and to offer most of the NFA patients the prospect of treatment which will provide a minimally affected QoL.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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