Endocrine Abstracts

The ‘European Young Endocrine Scientists’ (EYES) founded in 2011, is a committee under the patronage of the European Society of Endocinology (ESE). The primary goal of this committee is to increase the mutual exchange of ideas and knowledge between young endocrinologists – from basic researchers to clinicians – across Europe in the initial stages of their career. EYES enables young endocrinologists (<35 years) from all ESE member societies to actively c...

Insulin resistance and its resultant hyperinsulinaemia seem to play a pivotal role in the pathogenesis of polycystic ovary syndrome (PCOS), which apart from its cosmetic and metabolic consequences also lead to fertility problems. Therefore, metformin – a biguanide used as the first line of pharmacotherapy in patients with type 2 diabetes mellitus (T2DM), is often prescribed to women with PCOS in order to decrease the consequences of hyperinsulinaemia and to restore ovulat...

Major clinical events such as myocardial infarction and stroke are caused by atherosclerosis, a lipid-driven chronic inflammatory disease affecting the arterial wall. In recognition of the inflammatory drive in cardiovascular disease (CVD), a major interest has risen to complement current standards for high-risk patients by therapeutically targeting the inflammatory process. Prior to clinical application, therapeutic candidates are required to have a robust anti-inflammatory e...