Endocrine Abstracts

Methods: 157 patients (118 women and 39 men) aged from 30 to 73 years with radical treatment for Graves’ disease were included in this study. Patients were divided into two groups depending on a type of radical treatment: 76 patients have received radioiodine therapy, 81 persons received surgical treatment. Quality of life assessment was made by SF-36 questionnaire which includes eight scales: (physical functioning (PF), role physical functioning (RPF), pain (B), general health (GH), vital activity, social functioning (SF), role emotional functioning (REF), mental health (MH). The psychoemotional status was assessed by Spielberg-Khanin’s test and beck depression scale.

Results: Groups were comparable on a sex, age, period of follow-up after treatment, TSH levels, dose of levothyroxine. The median of indicators of Q&L on eight scales of the questionnaire in group of radio iodine fluctuated from 33.3 (role emotional functioning) to 62.5 (social functioning), points on a scale of a depression made 16 (13.5; 19), situational alarm 41.5 (36.5; 45), personal alarm 44 (36.5; 46). The median of indicators of Q&L in group with surgical treatment fluctuated from 40.8 (vital activity) to 62 (pain). Points on a scale of a depression made 15 (12; 18), situational alarm 44 (25; 60), personal alarm 44 (31; 67). There were no significant differences on all scales of a SF-36 questionare, level of alarm and a depression (P>0.05). However almost all indicators of quality of life in both groups were below average level, which can be caused by hypothyroidism.

Conclusion: Indicators of quality of life and the psychoemotional status of the patients who have received different types of radical treatment of Graves’ disease doesn’t depend on a type of radical treatment.