Endocrine Abstracts

Introduction: The majority of secreted hormones influence the whole body, its weigh and constitution as the results of ongoing metabolism. Scientific studies have reported the existence of relationship between the TSH and selected anthropometric parameters such as BMI or body weight.

Aim: The aim of the study was to assess the relationship between the value of TSH and selected anthropometric parameters in the group of endocrine patients.

Materials and methods: The study involved 87 patients with thyroid disorders who were admitted to the Endocrinology Department in 2013. We excluded patients treated with statins and patients with TSH values below 0.35 μIU/ml. Blood samples for TSH concentration were collected from patients in the morning. Anthropometric parameters were measurement in the morning in accordance with generally accepted methodology. The collected data were statistically analyzed, α=0.05.

Results: Mean age was 42.98±15.79 years. The mean concentration of TSH was 2.91±7.82 μIU/ml. The average value of waist circumference was 88.30±17.59 cm hip circumference 104.33±13.62 cm. The average BMI was 27.24±7.35 kg/m², WHR 0.84±0.10, and WHtR 53.99±10.59. The average percentage of body fat was 33.00±10.10%, lean body mass 47.59±10.96 kg, and muscle mass 44.71±11.31 kg. The average of the strength of hand was 30.36±9.00 kg. In the preliminary stage of the study we did not find any statistically significant correlation in TSH concentration and waist circumference (R=0.16; P=0.1221), loins circumference (R=−0,02; P=0.8023), BMI score (R=0.04; P=0.6873), percentage of body fat (R=0.01; P=0.8807), lean body mass (R=−0.01; P=0.8915) and muscle mass (R=−0.02; r=0.8296). There were observed positive significant correlation between the TSH concentration and WHR index (R=0.25; p=0.0160), and between TSH: WHtR ratio (R=0.21; P=0.0420). In addition the results showed a negative correlation between TSH concentration and the strength of hand (R=−0.24; P=0.0215).

Conslusions: The thyroid function (based on screening TSH exam) could affect body constitution and muscle strength. Enlargement of the studied group is necessary to confirm the observation.