ECE2014 Poster Presentations Obesity (53 abstracts)
Change in cardiovascular risk factors Following bariatric surgery for obesity – First Sri Lankan experience
Nayananjani Karunasena 1 , Thejana Wijeratne 2 , Uditha Bulugahapitiya 2 , Pubudu Chulasiri 3 , Kaushalya Kasturiaratchi 4 , Priyanthika Abeysinghe 2 & Waruni Abeysiri Gunawardana 2
1National Hospital of Sri Lanka, Colombo, Sri Lanka; 2Colombo South Teaching Hospital, Colombo, Sri Lanka; 3National Dengue Control Programme, Colombo, Sri Lanka; 4University Of Queensland, Brisbane, Queensland, Australia.
Introduction: Obesity is associated with increased prevalence of cardiovascular(CV) risk factors and mortality and the CV risk factors are known to reduce following bariatric surgery. The aim of this analysis was to determine the effect of bariatric surgery on CV risk factors and CV risk score.
Method: A prospective analytical study of the first 15 consecutive patients who underwent laparoscopic Sleeve Gastrectomy procedure from 2009 to 2011 in Colombo. Body weight, systolic (SBP) and diastolic (DBP) blood pressures and lipid profile were recorded preoperatively and at 1 year follow up. CV risk was calculated using Framingham’s CV risk score.
Results: Among the studied fifteen patients, 14 were females and one was male. Mean age was 40.07+/−10.93. Preoperative mean BMI was 45.1+/−8.09 and showed a 30.6% reduction (P<0.001) after 1 year following surgery. SBP showed a 11.2% reduction (P<0.01) and DBP reduction was 14.5% (P<0.01). Mean Triglyceride (TG) level showed a 21.1% reduction (P<0.05) and HDL cholesterol (HDL-C) level showed a 12.1% rise after 1 year from bariatric surgery. Total Cholesterol and LDL cholesterol levels did not show a significant reduction. CV risk score showed a 17.3% mean reduction at 1 year follow up, which was not statistically significant.
Conclusions: Cardiovascular risk factors, SBP, DBP, TG and HDL-C showed significant improvement following bariatric surgery. CV risk score showed a statistically non significant reduction after 1 year following bariatric surgery.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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